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{
    "metadata": {
        "accession": "PF02952",
        "entry_id": null,
        "type": "domain",
        "go_terms": null,
        "source_database": "pfam",
        "member_databases": null,
        "integrated": "IPR015888",
        "hierarchy": null,
        "name": {
            "name": "L-fucose isomerase, C-terminal domain",
            "short": "Fucose_iso_C"
        },
        "description": [
            {
                "text": "<p>L-fucose isomerase (5.3.1.25) converts the aldose L-fucose into the corresponding ketose L-fuculose during the first step in fucose metabolism using Mn2+ as a cofactor. The enzyme is a hexamer, forming the largest structurally known ketol isomerase, and each protomer consists of three domains. This entry represents the C-terminal domain.</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": [
            {
                "title": "L-fucose_isomerase",
                "extract": "<p>In enzymology, a <b>L-fucose isomerase</b> is an enzyme that catalyzes the chemical reaction</p><dl><dd>L-fucose <span class=\"mwe-math-element mwe-math-element-inline\"><img src=\"https://wikimedia.org/api/rest_v1/media/math/render/svg/1c37b981df851b9e54e489e017b1481e37d418f3\" class=\"mwe-math-fallback-image-inline mw-invert skin-invert\" aria-hidden=\"true\" style=\"vertical-align:-0.338ex;width:2.324ex;height:1.843ex\" /></span> L-fuculose</dd></dl>",
                "thumbnail": null
            }
        ],
        "literature": {
            "PUB00007428": {
                "PMID": 9367760,
                "ISBN": null,
                "volume": "273",
                "issue": "1",
                "year": 1997,
                "title": "Structure and mechanism of L-fucose isomerase from Escherichia coli.",
                "URL": null,
                "raw_pages": "256-68",
                "medline_journal": "J Mol Biol",
                "ISO_journal": "J. Mol. Biol.",
                "authors": [
                    "Seemann JE",
                    "Schulz GE."
                ],
                "DOI_URL": "http://dx.doi.org/10.1006/jmbi.1997.1280"
            }
        },
        "set_info": {
            "accession": "CL0866",
            "name": "ALR_C-like"
        },
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 11,
            "interactions": 0,
            "matches": 5174,
            "pathways": 0,
            "proteins": 5174,
            "proteomes": 2183,
            "sets": 1,
            "structural_models": {
                "alphafold": 4303,
                "bfvd": 0
            },
            "structures": 9,
            "taxa": 4717
        },
        "entry_annotations": {
            "hmm": 0,
            "logo": 0,
            "alignment:seed": 19,
            "alignment:full": 1739
        },
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}