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{
    "metadata": {
        "accession": "PF02769",
        "entry_id": null,
        "type": "domain",
        "go_terms": null,
        "source_database": "pfam",
        "member_databases": null,
        "integrated": "IPR010918",
        "hierarchy": null,
        "name": {
            "name": "AIR synthase related protein, C-terminal domain",
            "short": "AIRS_C"
        },
        "description": [
            {
                "text": "<p>This family includes Hydrogen expression/formation protein  HypE [swissprot:P24193], AIR synthases [swissprot:P08178] [ec:6.3.3.1], FGAM synthase [swissprot:P35852] [ec:6.3.5.3] and selenide, water dikinase [swissprot:P16456] [ec:2.7.9.3]. The function of the C-terminal domain of AIR synthase is unclear, but the cleft formed between N and C domains is postulated as a sulphate binding site [[cite:PUB00014643]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00014643": {
                "PMID": 10508786,
                "ISBN": null,
                "volume": "7",
                "issue": "9",
                "year": 1999,
                "title": "X-ray crystal structure of aminoimidazole ribonucleotide synthetase (PurM), from the Escherichia coli purine biosynthetic pathway at 2.5 A resolution.",
                "URL": null,
                "raw_pages": "1155-66",
                "medline_journal": "Structure",
                "ISO_journal": "Structure",
                "authors": [
                    "Li C",
                    "Kappock TJ",
                    "Stubbe J",
                    "Weaver TM",
                    "Ealick SE."
                ],
                "DOI_URL": "http://dx.doi.org/10.1016/S0969-2126(99)80182-8"
            }
        },
        "set_info": null,
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 452,
            "interactions": 0,
            "matches": 128844,
            "pathways": 0,
            "proteins": 101851,
            "proteomes": 20738,
            "sets": 0,
            "structural_models": {
                "alphafold": 71009,
                "bfvd": 11
            },
            "structures": 79,
            "taxa": 38613
        },
        "entry_annotations": {
            "hmm": 0,
            "logo": 0,
            "alignment:seed": 119,
            "alignment:full": 49709
        },
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": {
            "accession": "2zau",
            "name": "Crystal structure of an N-terminally truncated selenophosphate synthetase from Aquifex aeolicus"
        }
    }
}