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{
    "metadata": {
        "accession": "PF02362",
        "entry_id": null,
        "type": "family",
        "go_terms": null,
        "source_database": "pfam",
        "member_databases": null,
        "integrated": "IPR003340",
        "hierarchy": null,
        "name": {
            "name": "B3 DNA binding domain",
            "short": "B3"
        },
        "description": [
            {
                "text": "<p>This is a family of plant transcription factors with various roles in development, the aligned region corresponds the B3 DNA binding domain as described in [[cite:PUB00008122]] this domain is found in VP1/AB13 transcription factors [[cite:PUB00019193]].  Some proteins also have a second AP2 DNA binding domain [pfam:PF00847] such as RAV1 [swissprot:Q9ZWM9] [[cite:PUB00008122]]. DNA binding activity was demonstrated by [[cite:PUB00018332]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": [
            {
                "title": "B3_domain",
                "extract": "<p>The B3 DNA binding domain (DBD) is a highly conserved domain found exclusively in transcription factors combined with other domains. It consists of 100-120 residues, includes seven beta strands and two alpha helices that form a DNA-binding pseudobarrel protein fold ; it interacts with the major groove of DNA.</p>",
                "thumbnail": null
            }
        ],
        "literature": {
            "PUB00019193": {
                "PMID": 9188533,
                "ISBN": null,
                "volume": "276",
                "issue": "5320",
                "year": 1997,
                "title": "ARF1, a transcription factor that binds to auxin response elements.",
                "URL": null,
                "raw_pages": "1865-8",
                "medline_journal": "Science",
                "ISO_journal": "Science",
                "authors": [
                    "Ulmasov T",
                    "Hagen G",
                    "Guilfoyle TJ."
                ],
                "DOI_URL": "http://dx.doi.org/10.1126/science.276.5320.1865"
            },
            "PUB00008122": {
                "PMID": 9862967,
                "ISBN": null,
                "volume": "27",
                "issue": "2",
                "year": 1999,
                "title": "RAV1, a novel DNA-binding protein, binds to bipartite recognition sequence through two distinct DNA-binding domains uniquely found in higher plants.",
                "URL": null,
                "raw_pages": "470-8",
                "medline_journal": "Nucleic Acids Res",
                "ISO_journal": "Nucleic Acids Res.",
                "authors": [
                    "Kagaya Y",
                    "Ohmiya K",
                    "Hattori T."
                ],
                "DOI_URL": "http://dx.doi.org/10.1093/nar/27.2.470"
            },
            "PUB00018332": {
                "PMID": 9165754,
                "ISBN": null,
                "volume": "9",
                "issue": "5",
                "year": 1997,
                "title": "The conserved B3 domain of VIVIPAROUS1 has a cooperative DNA binding activity.",
                "URL": null,
                "raw_pages": "799-807",
                "medline_journal": "Plant Cell",
                "ISO_journal": "Plant Cell",
                "authors": [
                    "Suzuki M",
                    "Kao CY",
                    "McCarty DR."
                ],
                "DOI_URL": "http://dx.doi.org/10.1105/tpc.9.5.799"
            }
        },
        "set_info": {
            "accession": "CL0405",
            "name": "DNA_b-psBarrel"
        },
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 769,
            "interactions": 0,
            "matches": 66564,
            "pathways": 0,
            "proteins": 50203,
            "proteomes": 406,
            "sets": 1,
            "structural_models": {
                "alphafold": 43339,
                "bfvd": 0
            },
            "structures": 21,
            "taxa": 1472
        },
        "entry_annotations": {
            "hmm": 0,
            "logo": 0,
            "alignment:seed": 87,
            "alignment:full": 37961
        },
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": {
            "accession": "5os9",
            "name": "Structure of the B3 DNA-Binding Domain of NGA1"
        }
    }
}