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{
"metadata": {
"accession": "PF02362",
"entry_id": null,
"type": "family",
"go_terms": null,
"source_database": "pfam",
"member_databases": null,
"integrated": "IPR003340",
"hierarchy": null,
"name": {
"name": "B3 DNA binding domain",
"short": "B3"
},
"description": [
{
"text": "<p>This is a family of plant transcription factors with various roles in development, the aligned region corresponds the B3 DNA binding domain as described in [[cite:PUB00008122]] this domain is found in VP1/AB13 transcription factors [[cite:PUB00019193]]. Some proteins also have a second AP2 DNA binding domain [pfam:PF00847] such as RAV1 [swissprot:Q9ZWM9] [[cite:PUB00008122]]. DNA binding activity was demonstrated by [[cite:PUB00018332]].</p>",
"llm": false,
"checked": false,
"updated": false
}
],
"wikipedia": [
{
"title": "B3_domain",
"extract": "<p>The B3 DNA binding domain (DBD) is a highly conserved domain found exclusively in transcription factors combined with other domains. It consists of 100-120 residues, includes seven beta strands and two alpha helices that form a DNA-binding pseudobarrel protein fold ; it interacts with the major groove of DNA.</p>",
"thumbnail": null
}
],
"literature": {
"PUB00019193": {
"PMID": 9188533,
"ISBN": null,
"volume": "276",
"issue": "5320",
"year": 1997,
"title": "ARF1, a transcription factor that binds to auxin response elements.",
"URL": null,
"raw_pages": "1865-8",
"medline_journal": "Science",
"ISO_journal": "Science",
"authors": [
"Ulmasov T",
"Hagen G",
"Guilfoyle TJ."
],
"DOI_URL": "http://dx.doi.org/10.1126/science.276.5320.1865"
},
"PUB00008122": {
"PMID": 9862967,
"ISBN": null,
"volume": "27",
"issue": "2",
"year": 1999,
"title": "RAV1, a novel DNA-binding protein, binds to bipartite recognition sequence through two distinct DNA-binding domains uniquely found in higher plants.",
"URL": null,
"raw_pages": "470-8",
"medline_journal": "Nucleic Acids Res",
"ISO_journal": "Nucleic Acids Res.",
"authors": [
"Kagaya Y",
"Ohmiya K",
"Hattori T."
],
"DOI_URL": "http://dx.doi.org/10.1093/nar/27.2.470"
},
"PUB00018332": {
"PMID": 9165754,
"ISBN": null,
"volume": "9",
"issue": "5",
"year": 1997,
"title": "The conserved B3 domain of VIVIPAROUS1 has a cooperative DNA binding activity.",
"URL": null,
"raw_pages": "799-807",
"medline_journal": "Plant Cell",
"ISO_journal": "Plant Cell",
"authors": [
"Suzuki M",
"Kao CY",
"McCarty DR."
],
"DOI_URL": "http://dx.doi.org/10.1105/tpc.9.5.799"
}
},
"set_info": {
"accession": "CL0405",
"name": "DNA_b-psBarrel"
},
"overlaps_with": null,
"counters": {
"subfamilies": 0,
"domain_architectures": 769,
"interactions": 0,
"matches": 66564,
"pathways": 0,
"proteins": 50203,
"proteomes": 406,
"sets": 1,
"structural_models": {
"alphafold": 43339,
"bfvd": 0
},
"structures": 21,
"taxa": 1472
},
"entry_annotations": {
"hmm": 0,
"logo": 0,
"alignment:seed": 87,
"alignment:full": 37961
},
"cross_references": {},
"is_llm": false,
"is_reviewed_llm": false,
"is_updated_llm": false,
"representative_structure": {
"accession": "5os9",
"name": "Structure of the B3 DNA-Binding Domain of NGA1"
}
}
}