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{
    "metadata": {
        "accession": "PF01730",
        "entry_id": null,
        "type": "family",
        "go_terms": null,
        "source_database": "pfam",
        "member_databases": null,
        "integrated": "IPR002639",
        "hierarchy": null,
        "name": {
            "name": "UreF",
            "short": "UreF"
        },
        "description": [
            {
                "text": "<p>This family consists of the Urease accessory protein  UreF. The urease enzyme (urea amidohydrolase) hydrolyses urea into ammonia and carbamic acid [[cite:PUB00002304]].  UreF is proposed to modulate the activation process of urease by eliminating the binding of nickel irons to  noncarbamylated protein [[cite:PUB00002303]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00002304": {
                "PMID": 8550495,
                "ISBN": null,
                "volume": "178",
                "issue": "3",
                "year": 1996,
                "title": "Organization of Ureaplasma urealyticum urease gene cluster and expression in a suppressor strain of Escherichia coli.",
                "URL": null,
                "raw_pages": "647-55",
                "medline_journal": "J Bacteriol",
                "ISO_journal": "J. Bacteriol.",
                "authors": [
                    "Neyrolles O",
                    "Ferris S",
                    "Behbahani N",
                    "Montagnier L",
                    "Blanchard A."
                ],
                "DOI_URL": "http://ukpmc.ac.uk/picrender.cgi?tool=EBI&pubmedid=8550495&action=stream&blobtype=pdf"
            },
            "PUB00002303": {
                "PMID": 8808930,
                "ISBN": null,
                "volume": "178",
                "issue": "18",
                "year": 1996,
                "title": "Purification and activation properties of UreD-UreF-urease apoprotein complexes.",
                "URL": null,
                "raw_pages": "5417-21",
                "medline_journal": "J Bacteriol",
                "ISO_journal": "J. Bacteriol.",
                "authors": [
                    "Moncrief MB",
                    "Hausinger RP."
                ],
                "DOI_URL": "http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=EBI&pubmedid=8808930"
            }
        },
        "set_info": null,
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 43,
            "interactions": 0,
            "matches": 13164,
            "pathways": 0,
            "proteins": 13140,
            "proteomes": 8731,
            "sets": 0,
            "structural_models": {
                "alphafold": 9881,
                "bfvd": 0
            },
            "structures": 7,
            "taxa": 15380
        },
        "entry_annotations": {
            "hmm": 0,
            "logo": 0,
            "alignment:seed": 235,
            "alignment:full": 5234
        },
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": {
            "accession": "3o1q",
            "name": "Native Crystal Structure of Helicobacter pylori Urease Accessory Protein UreF"
        }
    }
}