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{
    "metadata": {
        "accession": "PTHR24216",
        "entry_id": null,
        "type": "family",
        "go_terms": null,
        "source_database": "panther",
        "member_databases": null,
        "integrated": null,
        "hierarchy": null,
        "name": {
            "name": "Cell Adhesion and Viral Modulation Protein",
            "short": "Cell_Adhesion-Viral_Mod"
        },
        "description": [
            {
                "text": "This family of proteins includes diverse members with various functions related to cellular and viral processes. Some proteins in this family are involved in cell adhesion and cytoskeletal organization, facilitating actin-membrane attachment at focal adhesion sites and recruiting other proteins to these sites. Other members are viral proteins that play roles in the viral life cycle, including capsid transport, uncoating, and modulation of host immune responses. These viral proteins can act as deneddylases, interfering with host cell cycle progression and promoting viral genome replication. They may also inhibit host defense mechanisms by affecting ubiquitination pathways and autophagy. Additionally, the family includes proteins that are structural components of extracellular matrices or involved in species-specific fertilization processes.",
                "llm": true,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": null,
        "set_info": null,
        "overlaps_with": null,
        "counters": {
            "subfamilies": 8,
            "domain_architectures": 0,
            "interactions": 0,
            "matches": 12477,
            "pathways": 0,
            "proteins": 12477,
            "proteomes": 3350,
            "sets": 0,
            "structural_models": {
                "alphafold": 7449,
                "bfvd": 7
            },
            "structures": 4,
            "taxa": 9593
        },
        "entry_annotations": {
            "hmm": 0,
            "logo": 0
        },
        "cross_references": {},
        "is_llm": true,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}