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{
    "metadata": {
        "accession": "PTHR15654",
        "entry_id": null,
        "type": "family",
        "go_terms": null,
        "source_database": "panther",
        "member_databases": null,
        "integrated": "IPR051885",
        "hierarchy": null,
        "name": {
            "name": "Coiled-coil domain-containing protein involved in ciliogenesis",
            "short": "CC_domain-Cilium_Assoc"
        },
        "description": [
            {
                "text": "This family of proteins includes components associated with centriolar satellites, which are crucial for primary cilium formation. The primary cilium is a microtubule-based organelle that extends from the surface of many vertebrate cells and is involved in signal transduction. The proteins in this family contain coiled-coil domains, which are known to facilitate protein-protein interactions. These interactions are essential for the assembly and stability of the centriolar satellites and thus play a significant role in the biogenesis of the primary cilium. The presence of these proteins in multiple species suggests a conserved function in ciliogenesis across different organisms.",
                "llm": true,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": null,
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        "counters": {
            "subfamilies": 2,
            "domain_architectures": 0,
            "interactions": 0,
            "matches": 2820,
            "pathways": 0,
            "proteins": 2820,
            "proteomes": 1030,
            "sets": 0,
            "structural_models": {
                "alphafold": 2559,
                "bfvd": 0
            },
            "structures": 7,
            "taxa": 3687
        },
        "entry_annotations": {
            "hmm": 0,
            "logo": 0
        },
        "cross_references": {},
        "is_llm": true,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}