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{
"metadata": {
"accession": "TIGR02254",
"entry_id": null,
"type": "family",
"go_terms": null,
"source_database": "ncbifam",
"member_databases": null,
"integrated": "IPR011951",
"hierarchy": null,
"name": {
"name": "noncanonical pyrimidine nucleotidase, YjjG family",
"short": "YjjG_YfnB"
},
"description": [
{
"text": "<p>This HAD superfamily includes including YjjG from E. coli and YfnB from B. subtilis. YjjG has been shown to act as a house-cleaning enzyme, cleaving nucleotides with non-canonical nucleotide bases. This family is a member of the haloacid dehalogenase (HAD) superfamily of hydrolases which are characterized by three conserved sequence motifs [2]. By virtue of an alpha helical domain in-between the first and second conserved motif, this family is a member of subfamily IA (TIGR01549).</p>",
"llm": false,
"checked": false,
"updated": false
}
],
"wikipedia": null,
"literature": {
"PUB00003337": {
"PMID": 7966317,
"ISBN": null,
"volume": "244",
"issue": "1",
"year": 1994,
"title": "Computer analysis of bacterial haloacid dehalogenases defines a large superfamily of hydrolases with diverse specificity. Application of an iterative approach to database search.",
"URL": null,
"raw_pages": "125-32",
"medline_journal": "J Mol Biol",
"ISO_journal": "J. Mol. Biol.",
"authors": [
"Koonin EV",
"Tatusov RL."
],
"DOI_URL": "http://dx.doi.org/10.1006/jmbi.1994.1711"
},
"PUB00070801": {
"PMID": 17286574,
"ISBN": null,
"volume": "270",
"issue": "1",
"year": 2007,
"title": "The Escherichia coli protein YjjG is a house-cleaning nucleotidase in vivo.",
"URL": null,
"raw_pages": "49-57",
"medline_journal": "FEMS Microbiol Lett",
"ISO_journal": "FEMS Microbiol. Lett.",
"authors": [
"Titz B",
"Hauser R",
"Engelbrecher A",
"Uetz P."
],
"DOI_URL": "http://dx.doi.org/10.1111/j.1574-6968.2007.00646.x"
}
},
"set_info": null,
"overlaps_with": null,
"counters": {
"subfamilies": 0,
"domain_architectures": 0,
"interactions": 0,
"matches": 7238,
"pathways": 0,
"proteins": 7238,
"proteomes": 4225,
"sets": 0,
"structural_models": {
"alphafold": 5673,
"bfvd": 0
},
"structures": 3,
"taxa": 7050
},
"entry_annotations": {
"hmm": 0,
"logo": 0
},
"cross_references": {},
"is_llm": false,
"is_reviewed_llm": false,
"is_updated_llm": false,
"representative_structure": {
"accession": "3qnm",
"name": "Haloalkane Dehalogenase Family Member from Bacteroides thetaiotaomicron of Unknown Function"
}
}
}
