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{
    "metadata": {
        "accession": "NF033433",
        "entry_id": null,
        "type": "domain",
        "go_terms": null,
        "source_database": "ncbifam",
        "member_databases": null,
        "integrated": null,
        "hierarchy": null,
        "name": {
            "name": "NisI/SpaI lantibiotic immunity lipoprotein domain",
            "short": "NisI_immun_dup"
        },
        "description": [
            {
                "text": "<p>This HMM describes a domain that occurs twice in the nisin lantibiotic self-immunity lipoprotein NisI, and once in the subtilin lantibiotic self-immunity lipoprotein SpaI, and once or twice in numerous other known or putative lantibiotic resistance lipoproteins.</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00105100": {
                "PMID": 26459561,
                "ISBN": null,
                "volume": "290",
                "issue": "48",
                "year": 2015,
                "title": "The Solution Structure of the Lantibiotic Immunity Protein NisI and Its Interactions with Nisin.",
                "URL": null,
                "raw_pages": "28869-86",
                "medline_journal": "J Biol Chem",
                "ISO_journal": "J Biol Chem",
                "authors": [
                    "Hacker C",
                    "Christ NA",
                    "Duchardt-Ferner E",
                    "Korn S",
                    "Gobl C",
                    "Berninger L",
                    "Dusterhus S",
                    "Hellmich UA",
                    "Madl T",
                    "Kotter P",
                    "Entian KD",
                    "Wohnert J."
                ],
                "DOI_URL": null
            },
            "PUB00091312": {
                "PMID": 22904324,
                "ISBN": null,
                "volume": "287",
                "issue": "42",
                "year": 2012,
                "title": "The First structure of a lantibiotic immunity protein, SpaI from Bacillus subtilis, reveals a novel fold.",
                "URL": null,
                "raw_pages": "35286-98",
                "medline_journal": "J Biol Chem",
                "ISO_journal": "J. Biol. Chem.",
                "authors": [
                    "Christ NA",
                    "Bochmann S",
                    "Gottstein D",
                    "Duchardt-Ferner E",
                    "Hellmich UA",
                    "Dusterhus S",
                    "Kotter P",
                    "Guntert P",
                    "Entian KD",
                    "Wohnert J."
                ],
                "DOI_URL": "https://doi.org/10.1074/jbc.M112.401620"
            }
        },
        "set_info": null,
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 0,
            "interactions": 0,
            "matches": 398,
            "pathways": 0,
            "proteins": 284,
            "proteomes": 104,
            "sets": 0,
            "structural_models": {
                "alphafold": 237,
                "bfvd": 0
            },
            "structures": 4,
            "taxa": 273
        },
        "entry_annotations": {
            "hmm": 0,
            "logo": 0
        },
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": {
            "accession": "5xhb",
            "name": "Crystal structure of the full length of NisI in a lipid free form, the nisin immunity protein, from Lactococcus lactis"
        }
    }
}