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{
"metadata": {
"accession": "cd19405",
"entry_id": null,
"type": "domain",
"go_terms": null,
"source_database": "cdd",
"member_databases": null,
"integrated": "IPR000381",
"hierarchy": null,
"name": {
"name": "transforming growth factor beta (TGF-beta) like domain found in inhibin beta B chain (INHBB) and similar proteins",
"short": "TGF_beta_INHBB"
},
"description": [
{
"text": "<p>INHBB, also termed activin beta-B chain, is a component of inhibin B, activin A, or activin AB. Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. [[cite:PUB00107523], [cite:PUB00107524], [cite:PUB00107525], [cite:PUB00107526], [cite:PUB00107527], [cite:PUB00107074]]</p>",
"llm": false,
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}
],
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"literature": {
"PUB00107527": {
"PMID": 12697670,
"ISBN": null,
"volume": "144",
"issue": "5",
"year": 2003,
"title": "Differential binding and neutralization of activins A and B by follistatin and follistatin like-3 (FSTL-3/FSRP/FLRG).",
"URL": null,
"raw_pages": "1671-4",
"medline_journal": "Endocrinology",
"ISO_journal": "Endocrinology",
"authors": [
"Schneyer A",
"Schoen A",
"Quigg A",
"Sidis Y."
],
"DOI_URL": null
},
"PUB00107526": {
"PMID": 2364091,
"ISBN": null,
"volume": "1039",
"issue": "2",
"year": 1990,
"title": "Purification and characterization of recombinant human activin B.",
"URL": null,
"raw_pages": "135-41",
"medline_journal": "Biochim Biophys Acta",
"ISO_journal": "Biochim Biophys Acta",
"authors": [
"Schmelzer CH",
"Burton LE",
"Tamony CM",
"Schwall RH",
"Mason AJ",
"Liegeois N."
],
"DOI_URL": null
},
"PUB00107074": {
"PMID": 27141051,
"ISBN": null,
"volume": "8",
"issue": "5",
"year": 2016,
"title": "TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology. ",
"URL": null,
"raw_pages": "a021873",
"medline_journal": "Cold Spring Harb Perspect Biol",
"ISO_journal": "Cold Spring Harb Perspect Biol",
"authors": [
"Morikawa M",
"Derynck R",
"Miyazono K."
],
"DOI_URL": null
},
"PUB00107523": {
"PMID": 2575216,
"ISBN": null,
"volume": "3",
"issue": "9",
"year": 1989,
"title": "Activin B: precursor sequences, genomic structure and in vitro activities.",
"URL": null,
"raw_pages": "1352-8",
"medline_journal": "Mol Endocrinol",
"ISO_journal": "Mol Endocrinol",
"authors": [
"Mason AJ",
"Berkemeier LM",
"Schmelzer CH",
"Schwall RH."
],
"DOI_URL": null
},
"PUB00107524": {
"PMID": 2739657,
"ISBN": null,
"volume": "3",
"issue": "6",
"year": 1989,
"title": "Characterization and regulation of testicular inhibin beta-subunit mRNA.",
"URL": null,
"raw_pages": "939-48",
"medline_journal": "Mol Endocrinol",
"ISO_journal": "Mol Endocrinol",
"authors": [
"Feng ZM",
"Bardin CW",
"Chen CL."
],
"DOI_URL": null
},
"PUB00107525": {
"PMID": 3754442,
"ISBN": null,
"volume": "135",
"issue": "3",
"year": 1986,
"title": "Structure of two human ovarian inhibins.",
"URL": null,
"raw_pages": "957-64",
"medline_journal": "Biochem Biophys Res Commun",
"ISO_journal": "Biochem Biophys Res Commun",
"authors": [
"Mason AJ",
"Niall HD",
"Seeburg PH."
],
"DOI_URL": null
}
},
"set_info": {
"accession": "cl40434",
"name": "TGF_beta_SF"
},
"overlaps_with": null,
"counters": {
"subfamilies": 0,
"domain_architectures": 0,
"interactions": 0,
"matches": 1018,
"pathways": 0,
"proteins": 1018,
"proteomes": 677,
"sets": 1,
"structural_models": {
"alphafold": 948,
"bfvd": 0
},
"structures": 0,
"taxa": 2105
},
"entry_annotations": {},
"cross_references": {},
"is_llm": false,
"is_reviewed_llm": false,
"is_updated_llm": false,
"representative_structure": null
}
}
