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{
"metadata": {
"accession": "cd18488",
"entry_id": null,
"type": "domain",
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"source_database": "cdd",
"member_databases": null,
"integrated": "IPR049737",
"hierarchy": null,
"name": {
"name": "BACK (BTB and C-terminal Kelch) domain found in BTB/POZ domain-containing proteins, BTBD3 and BTBD6",
"short": "BACK_BTBD3_like"
},
"description": [
{
"text": "<p>This subfamily includes BTB/POZ domain-containing proteins BTBD3 and BTBD6, both of which are BTB-domain-containing Kelch-like proteins. BTBD3 controls dendrite orientation toward active axons in mammalian neocortex. BTBD6 is required for proper embryogenesis and plays an essential evolutionarily-conserved role during neuronal development. [[cite:PUB00138927], [cite:PUB00138928], [cite:PUB00138929]]</p>",
"llm": false,
"checked": false,
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}
],
"wikipedia": null,
"literature": {
"PUB00138927": {
"PMID": 18855900,
"ISBN": null,
"volume": "237",
"issue": "11",
"year": 2008,
"title": "Xenopus BTBD6 and its Drosophila homologue lute are required for neuronal development.",
"URL": null,
"raw_pages": "3352-60",
"medline_journal": "Dev Dyn",
"ISO_journal": "Dev Dyn",
"authors": [
"Bury FJ",
"Moers V",
"Yan J",
"Souopgui J",
"Quan XJ",
"De Geest N",
"Kricha S",
"Hassan BA",
"Bellefroid EJ."
],
"DOI_URL": null
},
"PUB00138928": {
"PMID": 24179155,
"ISBN": null,
"volume": "342",
"issue": "6162",
"year": 2013,
"title": "BTBD3 controls dendrite orientation toward active axons in mammalian neocortex.",
"URL": null,
"raw_pages": "1114-8",
"medline_journal": "Science",
"ISO_journal": "Science",
"authors": [
"Matsui A",
"Tran M",
"Yoshida AC",
"Kikuchi SS",
"U M",
"Ogawa M",
"Shimogori T."
],
"DOI_URL": null
},
"PUB00138929": {
"PMID": 28789460,
"ISBN": null,
"volume": "14",
"issue": "2",
"year": 2017,
"title": "Preliminary investigation of the role of BTB domain-containing 3 gene in the proliferation and metastasis of hepatocellular carcinoma.",
"URL": null,
"raw_pages": "2505-2510",
"medline_journal": "Oncol Lett",
"ISO_journal": "Oncol Lett",
"authors": [
"Xiao W",
"Zhao W",
"Li L",
"Wu Q",
"Zhu L",
"Zhang Q",
"Dai W",
"Wang Y",
"Zhang B."
],
"DOI_URL": null
}
},
"set_info": {
"accession": "cl28903",
"name": "BACK"
},
"overlaps_with": null,
"counters": {
"subfamilies": 0,
"domain_architectures": 0,
"interactions": 0,
"matches": 783,
"pathways": 0,
"proteins": 783,
"proteomes": 411,
"sets": 1,
"structural_models": {
"alphafold": 717,
"bfvd": 0
},
"structures": 0,
"taxa": 1732
},
"entry_annotations": {},
"cross_references": {},
"is_llm": false,
"is_reviewed_llm": false,
"is_updated_llm": false,
"representative_structure": null
}
}
