GET /api/entry/cdd/CD14702/?format=api
HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept

{
    "metadata": {
        "accession": "cd14702",
        "entry_id": null,
        "type": "domain",
        "go_terms": null,
        "source_database": "cdd",
        "member_databases": null,
        "integrated": "IPR045314",
        "hierarchy": null,
        "name": {
            "name": "Basic leucine zipper (bZIP) domain of Plant G-box binding factor 1 (GBF1)-like transcription factors: a DNA-binding and dimerization domain",
            "short": "bZIP_plant_GBF1"
        },
        "description": [
            {
                "text": "<p>This subfamily is composed of plant bZIP transciption factors including Arabidopsis thaliana G-box binding factor 1 (GBF1), Zea mays Opaque-2 and Ocs element-binding factor 1 (OCSBF-1), Triticum aestivum Histone-specific transcription factor HBP1 (or HBP-1a), Petroselinum crispum Light-inducible protein CPRF3 and CPRF6, and Nicotiana tabacum BZI-3, among many others. bZIP G-box binding factors (GBFs) contain an N-terminal proline-rich domain in addition to the bZIP domain. GBFs are involved in developmental and physiological processes in response to stimuli such as light or hormones. Opaque-2 plays a role in affecting lysine content and carbohydrate metabolism, acting indirectly on starch/amino acid ratio. bZIP factors act in networks of homo and heterodimers in the regulation of a diverse set of cellular processes. The bZIP structural motif contains a basic region and a leucine zipper, composed of alpha helices with leucine residues 7 amino acids apart, which stabilize dimerization with a parallel leucine zipper domain. Dimerization of leucine zippers creates a pair of the adjacent basic regions that bind DNA and undergo conformational change. Dimerization occurs in a specific and predictable manner resulting in hundreds of dimers having unique effects on transcription. [[cite:PUB00098530], [cite:PUB00134032], [cite:PUB00019236], [cite:PUB00016443], [cite:PUB00098532], [cite:PUB00134033], [cite:PUB00134034], [cite:PUB00134035], [cite:PUB00097167], [cite:PUB00134036], [cite:PUB00134037], [cite:PUB00134038], [cite:PUB00134039], [cite:PUB00134040], [cite:PUB00134041], [cite:PUB00098531], [cite:PUB00098529], [cite:PUB00098528], [cite:PUB00134042], [cite:PUB00098533], [cite:PUB00134043], [cite:PUB00128138], [cite:PUB00128139], [cite:PUB00128137], [cite:PUB00004967]]</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00098529": {
                "PMID": 18930926,
                "ISBN": null,
                "volume": "283",
                "issue": "51",
                "year": 2008,
                "title": "GBF1, a transcription factor of blue light signaling in Arabidopsis, is degraded in the dark by a proteasome-mediated pathway independent of COP1 and SPA1.",
                "URL": null,
                "raw_pages": "35772-82",
                "medline_journal": "J Biol Chem",
                "ISO_journal": "J Biol Chem",
                "authors": [
                    "Mallappa C",
                    "Singh A",
                    "Ram H",
                    "Chattopadhyay S."
                ],
                "DOI_URL": null
            },
            "PUB00098531": {
                "PMID": 19076690,
                "ISBN": null,
                "volume": "145",
                "issue": "5",
                "year": 2008,
                "title": "Heterofertilization of the opaque-2 endosperm in maize.",
                "URL": null,
                "raw_pages": "225-30",
                "medline_journal": "Hereditas",
                "ISO_journal": "Hereditas",
                "authors": [
                    "Yang W",
                    "Zheng Y",
                    "Wu J."
                ],
                "DOI_URL": null
            },
            "PUB00134037": {
                "PMID": 22138577,
                "ISBN": null,
                "volume": "14",
                "issue": "1",
                "year": 2011,
                "title": "Polarized cell growth in Arabidopsis requires endosomal recycling mediated by GBF1-related ARF exchange factors.",
                "URL": null,
                "raw_pages": "80-6",
                "medline_journal": "Nat Cell Biol",
                "ISO_journal": "Nat Cell Biol",
                "authors": [
                    "Richter S",
                    "Muller LM",
                    "Stierhof YD",
                    "Mayer U",
                    "Takada N",
                    "Kost B",
                    "Vieten A",
                    "Geldner N",
                    "Koncz C",
                    "Jurgens G."
                ],
                "DOI_URL": null
            },
            "PUB00134042": {
                "PMID": 12657652,
                "ISBN": null,
                "volume": "278",
                "issue": "23",
                "year": 2003,
                "title": "Synergistic activation of seed storage protein gene expression in Arabidopsis by ABI3 and two bZIPs related to OPAQUE2.",
                "URL": null,
                "raw_pages": "21003-11",
                "medline_journal": "J Biol Chem",
                "ISO_journal": "J Biol Chem",
                "authors": [
                    "Lara P",
                    "Onate-Sanchez L",
                    "Abraham Z",
                    "Ferrandiz C",
                    "Diaz I",
                    "Carbonero P",
                    "Vicente-Carbajosa J."
                ],
                "DOI_URL": null
            },
            "PUB00134034": {
                "PMID": 22937104,
                "ISBN": null,
                "volume": "7",
                "issue": "8",
                "year": 2012,
                "title": "Zea mays Taxilin protein negatively regulates opaque-2 transcriptional activity by causing a change in its sub-cellular distribution.",
                "URL": null,
                "raw_pages": "e43822",
                "medline_journal": "PLoS One",
                "ISO_journal": "PLoS One",
                "authors": [
                    "Zhang N",
                    "Qiao Z",
                    "Liang Z",
                    "Mei B",
                    "Xu Z",
                    "Song R."
                ],
                "DOI_URL": null
            },
            "PUB00134043": {
                "PMID": 11523788,
                "ISBN": null,
                "volume": "265",
                "issue": "6",
                "year": 2001,
                "title": "Isolation and characterization of four novel parsley proteins that interact with the transcriptional regulators CPRF1 and CPRF2.",
                "URL": null,
                "raw_pages": "964-76",
                "medline_journal": "Mol Genet Genomics",
                "ISO_journal": "Mol Genet Genomics",
                "authors": [
                    "Rugner A",
                    "Frohnmeyer H",
                    "Nake C",
                    "Wellmer F",
                    "Kircher S",
                    "Schafer E",
                    "Harter K."
                ],
                "DOI_URL": null
            },
            "PUB00098530": {
                "PMID": 18424222,
                "ISBN": null,
                "volume": "13",
                "issue": "5",
                "year": 2008,
                "title": "Post-translational regulation of plant bZIP factors.",
                "URL": null,
                "raw_pages": "247-55",
                "medline_journal": "Trends Plant Sci",
                "ISO_journal": "Trends Plant Sci",
                "authors": [
                    "Schutze K",
                    "Harter K",
                    "Chaban C."
                ],
                "DOI_URL": null
            },
            "PUB00004967": {
                "PMID": 7780801,
                "ISBN": null,
                "volume": "2",
                "issue": "2",
                "year": 1995,
                "title": "Transcription factors 1: bZIP proteins.",
                "URL": null,
                "raw_pages": "101-68",
                "medline_journal": "Protein Profile",
                "ISO_journal": null,
                "authors": [
                    "Hurst HC."
                ],
                "DOI_URL": null
            },
            "PUB00098528": {
                "PMID": 18365246,
                "ISBN": null,
                "volume": "228",
                "issue": "2",
                "year": 2008,
                "title": "Soybean GmbZIP44, GmbZIP62 and GmbZIP78 genes function as negative regulator of ABA signaling and confer salt and freezing tolerance in transgenic Arabidopsis.",
                "URL": null,
                "raw_pages": "225-40",
                "medline_journal": "Planta",
                "ISO_journal": "Planta",
                "authors": [
                    "Liao Y",
                    "Zou HF",
                    "Wei W",
                    "Hao YJ",
                    "Tian AG",
                    "Huang J",
                    "Liu YF",
                    "Zhang JS",
                    "Chen SY."
                ],
                "DOI_URL": null
            },
            "PUB00098533": {
                "PMID": 11737777,
                "ISBN": null,
                "volume": "28",
                "issue": "4",
                "year": 2001,
                "title": "BZI-1 specifically heterodimerises with the tobacco bZIP transcription factors BZI-2, BZI-3/TBZF and BZI-4, and is functionally involved in flower development.",
                "URL": null,
                "raw_pages": "397-408",
                "medline_journal": "Plant J",
                "ISO_journal": "Plant J",
                "authors": [
                    "Strathmann A",
                    "Kuhlmann M",
                    "Heinekamp T",
                    "Droge-Laser W."
                ],
                "DOI_URL": null
            },
            "PUB00128137": {
                "PMID": 8504253,
                "ISBN": null,
                "volume": "3",
                "issue": "2",
                "year": 1993,
                "title": "Interactions of coiled coils in transcription factors: where is the specificity?",
                "URL": null,
                "raw_pages": "278-85",
                "medline_journal": "Curr Opin Genet Dev",
                "ISO_journal": "Curr Opin Genet Dev",
                "authors": [
                    "Baxevanis AD",
                    "Vinson CR."
                ],
                "DOI_URL": null
            },
            "PUB00134040": {
                "PMID": 19853962,
                "ISBN": null,
                "volume": "167",
                "issue": "3",
                "year": 2010,
                "title": "A novel bZIP gene from Tamarix hispida mediates physiological responses to salt stress in tobacco plants.",
                "URL": null,
                "raw_pages": "222-30",
                "medline_journal": "J Plant Physiol",
                "ISO_journal": "J Plant Physiol",
                "authors": [
                    "Wang Y",
                    "Gao C",
                    "Liang Y",
                    "Wang C",
                    "Yang C",
                    "Liu G."
                ],
                "DOI_URL": null
            },
            "PUB00016443": {
                "PMID": 11722549,
                "ISBN": null,
                "volume": "268",
                "issue": "22",
                "year": 2001,
                "title": "Plant bZIP G-box binding factors. Modular structure and activation mechanisms.",
                "URL": null,
                "raw_pages": "5655-66",
                "medline_journal": "Eur J Biochem",
                "ISO_journal": "Eur. J. Biochem.",
                "authors": [
                    "Siberil Y",
                    "Doireau P",
                    "Gantet P."
                ],
                "DOI_URL": "http://dx.doi.org/10.1046/j.0014-2956.2001.02552.x"
            },
            "PUB00134041": {
                "PMID": 19825579,
                "ISBN": null,
                "volume": "1",
                "issue": "5",
                "year": 2008,
                "title": "Diverged copies of the seed regulatory Opaque-2 gene by a segmental duplication in the progenitor genome of rice, sorghum, and maize.",
                "URL": null,
                "raw_pages": "760-9",
                "medline_journal": "Mol Plant",
                "ISO_journal": "Mol Plant",
                "authors": [
                    "Xu JH",
                    "Messing J."
                ],
                "DOI_URL": null
            },
            "PUB00134035": {
                "PMID": 22766018,
                "ISBN": null,
                "volume": "129",
                "issue": "9-12",
                "year": 2012,
                "title": "HY1 genetically interacts with GBF1 and regulates the activity of the Z-box containing promoters in light signaling pathways in Arabidopsis thaliana.",
                "URL": null,
                "raw_pages": "298-307",
                "medline_journal": "Mech Dev",
                "ISO_journal": "Mech Dev",
                "authors": [
                    "Prasad VB",
                    "Gupta N",
                    "Nandi A",
                    "Chattopadhyay S."
                ],
                "DOI_URL": null
            },
            "PUB00097167": {
                "PMID": 22718771,
                "ISBN": null,
                "volume": "287",
                "issue": "33",
                "year": 2012,
                "title": "Redox-mediated mechanisms regulate DNA binding activity of the G-group of basic region leucine zipper (bZIP) transcription factors in Arabidopsis.",
                "URL": null,
                "raw_pages": "27510-25",
                "medline_journal": "J Biol Chem",
                "ISO_journal": "J Biol Chem",
                "authors": [
                    "Shaikhali J",
                    "Noren L",
                    "de Dios Barajas-Lopez J",
                    "Srivastava V",
                    "Konig J",
                    "Sauer UH",
                    "Wingsle G",
                    "Dietz KJ",
                    "Strand A."
                ],
                "DOI_URL": null
            },
            "PUB00134038": {
                "PMID": 21241522,
                "ISBN": null,
                "volume": "12",
                "issue": null,
                "year": 2011,
                "title": "The Zea mays mutants opaque-2 and opaque-7 disclose extensive changes in endosperm metabolism as revealed by protein, amino acid, and transcriptome-wide analyses.",
                "URL": null,
                "raw_pages": "41",
                "medline_journal": "BMC Genomics",
                "ISO_journal": "BMC Genomics",
                "authors": [
                    "Hartings H",
                    "Lauria M",
                    "Lazzaroni N",
                    "Pirona R",
                    "Motto M."
                ],
                "DOI_URL": null
            },
            "PUB00134032": {
                "PMID": 18926491,
                "ISBN": null,
                "volume": "331",
                "issue": "10",
                "year": 2008,
                "title": "Molecular and biochemical mechanisms in maize endosperm development: the role of pyruvate-Pi-dikinase and Opaque-2 in the control of C/N ratio.",
                "URL": null,
                "raw_pages": "772-9",
                "medline_journal": "C R Biol",
                "ISO_journal": "C R Biol",
                "authors": [
                    "Prioul JL",
                    "Mechin V",
                    "Damerval C."
                ],
                "DOI_URL": null
            },
            "PUB00128139": {
                "PMID": 16580748,
                "ISBN": null,
                "volume": "1759",
                "issue": "1-2",
                "year": 2006,
                "title": "Deciphering B-ZIP transcription factor interactions in vitro and in vivo.",
                "URL": null,
                "raw_pages": "4-12",
                "medline_journal": "Biochim Biophys Acta",
                "ISO_journal": "Biochim Biophys Acta",
                "authors": [
                    "Vinson C",
                    "Acharya A",
                    "Taparowsky EJ."
                ],
                "DOI_URL": null
            },
            "PUB00098532": {
                "PMID": 23457531,
                "ISBN": null,
                "volume": "8",
                "issue": "2",
                "year": 2013,
                "title": "Increasing lysine content of waxy maize through introgression of opaque-2 and opaque-16 genes using molecular assisted and biochemical development.",
                "URL": null,
                "raw_pages": "e56227",
                "medline_journal": "PLoS One",
                "ISO_journal": "PLoS One",
                "authors": [
                    "Zhang W",
                    "Yang W",
                    "Wang M",
                    "Wang W",
                    "Zeng G",
                    "Chen Z",
                    "Cai Y."
                ],
                "DOI_URL": null
            },
            "PUB00134036": {
                "PMID": 22692212,
                "ISBN": null,
                "volume": "287",
                "issue": "31",
                "year": 2012,
                "title": "Molecular interactions of GBF1 with HY5 and HYH proteins during light-mediated seedling development in Arabidopsis thaliana.",
                "URL": null,
                "raw_pages": "25995-6009",
                "medline_journal": "J Biol Chem",
                "ISO_journal": "J Biol Chem",
                "authors": [
                    "Singh A",
                    "Ram H",
                    "Abbas N",
                    "Chattopadhyay S."
                ],
                "DOI_URL": null
            },
            "PUB00019236": {
                "PMID": 11906833,
                "ISBN": null,
                "volume": "7",
                "issue": "3",
                "year": 2002,
                "title": "bZIP transcription factors in Arabidopsis.",
                "URL": null,
                "raw_pages": "106-11",
                "medline_journal": "Trends Plant Sci",
                "ISO_journal": "Trends Plant Sci.",
                "authors": [
                    "Jakoby M",
                    "Weisshaar B",
                    "Droge-Laser W",
                    "Vicente-Carbajosa J",
                    "Tiedemann J",
                    "Kroj T",
                    "Parcy F; bZIP Research Group."
                ],
                "DOI_URL": "http://dx.doi.org/10.1016/S1360-1385(01)02223-3"
            },
            "PUB00134039": {
                "PMID": 20484024,
                "ISBN": null,
                "volume": "153",
                "issue": "3",
                "year": 2010,
                "title": "G-Box binding factor1 reduces CATALASE2 expression and regulates the onset of leaf senescence in Arabidopsis.",
                "URL": null,
                "raw_pages": "1321-31",
                "medline_journal": "Plant Physiol",
                "ISO_journal": "Plant Physiol",
                "authors": [
                    "Smykowski A",
                    "Zimmermann P",
                    "Zentgraf U."
                ],
                "DOI_URL": null
            },
            "PUB00128138": {
                "PMID": 16731568,
                "ISBN": null,
                "volume": "23",
                "issue": "8",
                "year": 2006,
                "title": "Cross-species annotation of basic leucine zipper factor interactions: Insight into the evolution of closed interaction networks.",
                "URL": null,
                "raw_pages": "1480-92",
                "medline_journal": "Mol Biol Evol",
                "ISO_journal": "Mol Biol Evol",
                "authors": [
                    "Deppmann CD",
                    "Alvania RS",
                    "Taparowsky EJ."
                ],
                "DOI_URL": null
            },
            "PUB00134033": {
                "PMID": 23144545,
                "ISBN": null,
                "volume": "8",
                "issue": "18",
                "year": 2012,
                "title": "Computational predictions of common transcription factor binding sites on the genes of proline metabolism in plants.",
                "URL": null,
                "raw_pages": "886-90",
                "medline_journal": "Bioinformation",
                "ISO_journal": "Bioinformation",
                "authors": [
                    "Kiran U",
                    "Abdin MZ."
                ],
                "DOI_URL": null
            }
        },
        "set_info": {
            "accession": "cl21462",
            "name": "bZIP"
        },
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 0,
            "interactions": 0,
            "matches": 13138,
            "pathways": 0,
            "proteins": 13134,
            "proteomes": 421,
            "sets": 1,
            "structural_models": {
                "alphafold": 11534,
                "bfvd": 0
            },
            "structures": 0,
            "taxa": 1440
        },
        "entry_annotations": {},
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}