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{
    "metadata": {
        "accession": "cd12225",
        "entry_id": null,
        "type": "domain",
        "go_terms": null,
        "source_database": "cdd",
        "member_databases": null,
        "integrated": null,
        "hierarchy": null,
        "name": {
            "name": "RNA recognition motif 1 and 2 (RRM1, RRM2) found in Arabidopsis thaliana CTC-interacting domain protein CID8, CID9, CID10, CID11, CID12, CID 13 and similar proteins",
            "short": "RRM1_2_CID8_like"
        },
        "description": [
            {
                "text": "<p>This subgroup corresponds to the RRM domains found in A. thaliana CID8, CID9, CID10, CID11, CID12, CID 13 and mainly their plant homologs. These highly related RNA-binding proteins contain an N-terminal PAM2 domain (PABP-interacting motif 2), two RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains), and a basic region that resembles a bipartite nuclear localization signal. The biological role of this family remains unclear. [[cite:PUB00067313], [cite:PUB00084471], [cite:PUB00079469], [cite:PUB00079470]]</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00084471": {
                "PMID": 9177318,
                "ISBN": null,
                "volume": "34",
                "issue": "1",
                "year": 1997,
                "title": "A new Arabidopsis nucleic-acid-binding protein gene is highly expressed in dividing cells during development.",
                "URL": null,
                "raw_pages": "119-24",
                "medline_journal": "Plant Mol Biol",
                "ISO_journal": "Plant Mol. Biol.",
                "authors": [
                    "Hecht V",
                    "Stiefel V",
                    "Delseny M",
                    "Gallois P."
                ],
                "DOI_URL": "http://dx.doi.org/10.1023/A:1005834402536"
            },
            "PUB00067313": {
                "PMID": 15650869,
                "ISBN": null,
                "volume": "272",
                "issue": "6",
                "year": 2005,
                "title": "Four distinct classes of proteins as interaction partners of the PABC domain of Arabidopsis thaliana Poly(A)-binding proteins.",
                "URL": null,
                "raw_pages": "651-65",
                "medline_journal": "Mol Genet Genomics",
                "ISO_journal": "Mol. Genet. Genomics",
                "authors": [
                    "Bravo J",
                    "Aguilar-Henonin L",
                    "Olmedo G",
                    "Guzman P."
                ],
                "DOI_URL": "http://dx.doi.org/10.1007/s00438-004-1090-9"
            },
            "PUB00079470": {
                "PMID": 22278943,
                "ISBN": null,
                "volume": "3",
                "issue": "2",
                "year": 2012,
                "title": "Structural insight into RNA recognition motifs: versatile molecular Lego building blocks for biological systems.",
                "URL": null,
                "raw_pages": "229-46",
                "medline_journal": "Wiley Interdiscip Rev RNA",
                "ISO_journal": "Wiley Interdiscip Rev RNA",
                "authors": [
                    "Muto Y",
                    "Yokoyama S."
                ],
                "DOI_URL": "http://dx.doi.org/10.1002/wrna.1107"
            },
            "PUB00079469": {
                "PMID": 22516180,
                "ISBN": null,
                "volume": "22",
                "issue": "3",
                "year": 2012,
                "title": "Dynamics in multi-domain protein recognition of RNA.",
                "URL": null,
                "raw_pages": "287-96",
                "medline_journal": "Curr Opin Struct Biol",
                "ISO_journal": "Curr. Opin. Struct. Biol.",
                "authors": [
                    "Mackereth CD",
                    "Sattler M."
                ],
                "DOI_URL": "http://dx.doi.org/10.1016/j.sbi.2012.03.013"
            }
        },
        "set_info": {
            "accession": "cl17169",
            "name": "RRM_SF"
        },
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 0,
            "interactions": 0,
            "matches": 9,
            "pathways": 0,
            "proteins": 9,
            "proteomes": 6,
            "sets": 1,
            "structural_models": {
                "alphafold": 8,
                "bfvd": 0
            },
            "structures": 0,
            "taxa": 27
        },
        "entry_annotations": {},
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}