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{
"metadata": {
"accession": "cd10317",
"entry_id": null,
"type": "domain",
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"source_database": "cdd",
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"name": {
"name": "C-terminal domain of rhamnogalacturonan lyase, a family 4 polysaccharide lyase",
"short": "RGL4_C"
},
"description": [
{
"text": "<p>The rhamnogalacturonan lyase of the polysaccharide lyase family 4 (RGL4) is involved in the degradation of RG (rhamnogalacturonan) type-I, an important pectic plant cell wall polysaccharide, by cleaving the alpha-1,4 glycoside bond between L-rhamnose and D-galacturonic acids in the backbone of RG type-I through a beta-elimination reaction. RGL4 consists of three domains, an N-terminal catalytic domain, a middle domain with a FNIII type fold and a C-terminal domain with a jelly roll fold. Both the middle and the C-terminal domain are putative carbohydrate binding modules. There are two types of RG lyases, which both cleave the alpha-1,4 bonds of the RG-I main chain (RG chain) through the beta-elimination reaction, but belong to two structurally unrelated polysaccharide lyase (PL) families, 4 and 11. [[cite:PUB00083824], [cite:PUB00027701], [cite:PUB00083820], [cite:PUB00083822], [cite:PUB00083823]]</p>",
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"literature": {
"PUB00083823": {
"PMID": 7654407,
"ISBN": null,
"volume": "16",
"issue": "4",
"year": 1995,
"title": "Polysaccharide lyases.",
"URL": null,
"raw_pages": "323-47",
"medline_journal": "FEMS Microbiol Rev",
"ISO_journal": "FEMS Microbiol. Rev.",
"authors": [
"Sutherland IW."
],
"DOI_URL": "http://dx.doi.org/10.1111/j.1574-6976.1995.tb00179.x"
},
"PUB00083822": {
"PMID": 15224891,
"ISBN": null,
"volume": "23",
"issue": "4",
"year": 2003,
"title": "Polysaccharide lyases: recent developments as biotechnological tools.",
"URL": null,
"raw_pages": "233-66",
"medline_journal": "Crit Rev Biotechnol",
"ISO_journal": "Crit. Rev. Biotechnol.",
"authors": [
"Michaud P",
"Da Costa A",
"Courtois B",
"Courtois J."
],
"DOI_URL": "http://dx.doi.org/10.1080/07388550390447043"
},
"PUB00083824": {
"PMID": 20925655,
"ISBN": null,
"volume": "432",
"issue": "3",
"year": 2010,
"title": "A hierarchical classification of polysaccharide lyases for glycogenomics.",
"URL": null,
"raw_pages": "437-44",
"medline_journal": "Biochem J",
"ISO_journal": "Biochem. J.",
"authors": [
"Lombard V",
"Bernard T",
"Rancurel C",
"Brumer H",
"Coutinho PM",
"Henrissat B."
],
"DOI_URL": "http://dx.doi.org/10.1042/BJ20101185"
},
"PUB00083820": {
"PMID": 10907797,
"ISBN": null,
"volume": "35",
"issue": "3",
"year": 2000,
"title": "Structural and functional comparison of polysaccharide-degrading enzymes.",
"URL": null,
"raw_pages": "221-51",
"medline_journal": "Crit Rev Biochem Mol Biol",
"ISO_journal": "Crit. Rev. Biochem. Mol. Biol.",
"authors": [
"Jedrzejas MJ."
],
"DOI_URL": "http://dx.doi.org/10.1080/10409230091169195"
},
"PUB00027701": {
"PMID": 15135077,
"ISBN": null,
"volume": "565",
"issue": "1-3",
"year": 2004,
"title": "Rhamnogalacturonan lyase reveals a unique three-domain modular structure for polysaccharide lyase family 4.",
"URL": null,
"raw_pages": "188-94",
"medline_journal": "FEBS Lett",
"ISO_journal": "FEBS Lett.",
"authors": [
"McDonough MA",
"Kadirvelraj R",
"Harris P",
"Poulsen JC",
"Larsen S."
],
"DOI_URL": "http://dx.doi.org/10.1016/j.febslet.2004.03.094"
}
},
"set_info": {
"accession": "cl15687",
"name": "RGL4_C"
},
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"matches": 6164,
"pathways": 0,
"proteins": 6020,
"proteomes": 1443,
"sets": 1,
"structural_models": {
"alphafold": 4979,
"bfvd": 0
},
"structures": 4,
"taxa": 3260
},
"entry_annotations": {},
"cross_references": {},
"is_llm": false,
"is_reviewed_llm": false,
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"representative_structure": null
}
}
