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{
"metadata": {
"accession": "cd00829",
"entry_id": null,
"type": "domain",
"go_terms": null,
"source_database": "cdd",
"member_databases": null,
"integrated": null,
"hierarchy": null,
"name": {
"name": null,
"short": "SCP-x_thiolase"
},
"description": [
{
"text": "<p>Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein. [[cite:PUB00114043], [cite:PUB00114046], [cite:PUB00114047], [cite:PUB00114048]]</p>",
"llm": false,
"checked": false,
"updated": false
}
],
"wikipedia": null,
"literature": {
"PUB00114048": {
"PMID": 10709653,
"ISBN": null,
"volume": "466",
"issue": null,
"year": 1999,
"title": "Role and organization of peroxisomal beta-oxidation.",
"URL": null,
"raw_pages": "261-72",
"medline_journal": "Adv Exp Med Biol",
"ISO_journal": "Adv Exp Med Biol",
"authors": [
"Van Veldhoven PP",
"Mannaerts GP."
],
"DOI_URL": null
},
"PUB00114046": {
"PMID": 11591437,
"ISBN": null,
"volume": "40",
"issue": "6",
"year": 2001,
"title": "Gene structure, intracellular localization, and functional roles of sterol carrier protein-2.",
"URL": null,
"raw_pages": "498-563",
"medline_journal": "Prog Lipid Res",
"ISO_journal": "Prog Lipid Res",
"authors": [
"Gallegos AM",
"Atshaves BP",
"Storey SM",
"Starodub O",
"Petrescu AD",
"Huang H",
"McIntosh AL",
"Martin GG",
"Chao H",
"Kier AB",
"Schroeder F."
],
"DOI_URL": null
},
"PUB00114047": {
"PMID": 10856712,
"ISBN": null,
"volume": "1486",
"issue": "1",
"year": 2000,
"title": "Sterol carrier protein-2.",
"URL": null,
"raw_pages": "45-54",
"medline_journal": "Biochim Biophys Acta",
"ISO_journal": "Biochim Biophys Acta",
"authors": [
"Seedorf U",
"Ellinghaus P",
"Roch Nofer J."
],
"DOI_URL": null
},
"PUB00114043": {
"PMID": 11915938,
"ISBN": null,
"volume": "59",
"issue": "2",
"year": 2002,
"title": "Sterol carrier protein-2: structure reveals function.",
"URL": null,
"raw_pages": "193-212",
"medline_journal": "Cell Mol Life Sci",
"ISO_journal": "Cell Mol Life Sci",
"authors": [
"Stolowich NJ",
"Petrescu AD",
"Huang H",
"Martin GG",
"Scott AI",
"Schroeder F."
],
"DOI_URL": null
}
},
"set_info": {
"accession": "cl09938",
"name": "cond_enzymes"
},
"overlaps_with": null,
"counters": {
"subfamilies": 0,
"domain_architectures": 0,
"interactions": 0,
"matches": 30639,
"pathways": 0,
"proteins": 30635,
"proteomes": 7050,
"sets": 1,
"structural_models": {
"alphafold": 23021,
"bfvd": 0
},
"structures": 24,
"taxa": 13621
},
"entry_annotations": {},
"cross_references": {},
"is_llm": false,
"is_reviewed_llm": false,
"is_updated_llm": false,
"representative_structure": {
"accession": "4yzo",
"name": "Crystal Structure Analysis of Thiolase-like protein, ST0096 from Sulfolobus Tokodaii"
}
}
}
