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{
"metadata": {
"accession": "G3DSA:3.90.1590.10",
"entry_id": null,
"type": "homologous_superfamily",
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"source_database": "cathgene3d",
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"name": {
"name": "Glutathione-dependent formaldehyde-activating enzyme superfamily",
"short": "Gfa_activating_sf"
},
"description": [
{
"text": "This superfamily of proteins is involved in the detoxification process. Members of this superfamily catalyze a reaction that combines formaldehyde, a toxic compound, with glutathione, resulting in the formation of a less harmful product. This enzymatic activity is crucial for organisms to mitigate the effects of formaldehyde exposure, which can occur through various metabolic processes or environmental sources. The reaction product, S-hydroxymethylglutathione, is subsequently processed by other enzymes to further reduce toxicity and facilitate excretion or recycling of the components.",
"llm": true,
"checked": false,
"updated": false
}
],
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"matches": 38743,
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"proteins": 37361,
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"structural_models": {
"alphafold": 29533,
"bfvd": 1
},
"structures": 3,
"taxa": 11997
},
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"is_llm": true,
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"representative_structure": {
"accession": "8ajq",
"name": "Crystal structure of PA2722 from Pseudomonas aeruginosa PAO1"
}
}
}