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{
    "metadata": {
        "accession": "IPR056779",
        "entry_id": null,
        "type": "domain",
        "go_terms": null,
        "source_database": "interpro",
        "member_databases": {
            "pfam": {
                "PF25038": "Csf1 family C-terminal region"
            }
        },
        "integrated": null,
        "hierarchy": {
            "accession": "IPR056779",
            "name": "Csf1, C-terminal region",
            "type": "Domain",
            "children": []
        },
        "name": {
            "name": "Csf1, C-terminal region",
            "short": "Csf1_C"
        },
        "description": [
            {
                "text": "<p>This entry represents the C-terminal region of Csf1.</p>",
                "llm": false,
                "checked": false,
                "updated": false
            },
            {
                "text": "<p>This entry includes Csf1 protein from yeast, which is the orthologue of human BLTP1. These are tube-forming lipid transport proteins which provide phosphatidylethanolamine for glycosylphosphatidylinositol (GPI) anchor synthesis in the endoplasmic reticulum [[cite:PUB00101862]]. They belong to the repeating β-groove (RBG) superfamily which are conserved lipid transfer proteins containing long hydrophobic grooves consisting of multiple repeating modules made of five β-sheets followed by a loop [[cite:PUB00101861]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00101861": {
                "PMID": 35491307,
                "ISBN": null,
                "volume": "32",
                "issue": "11",
                "year": 2022,
                "title": "A novel superfamily of bridge-like lipid transfer proteins.",
                "URL": null,
                "raw_pages": "962-974",
                "medline_journal": "Trends Cell Biol",
                "ISO_journal": "Trends Cell Biol",
                "authors": [
                    "Neuman SD",
                    "Levine TP",
                    "Bashirullah A."
                ],
                "DOI_URL": null
            },
            "PUB00101862": {
                "PMID": 35015055,
                "ISBN": null,
                "volume": "221",
                "issue": "3",
                "year": 2022,
                "title": "Vps13-like proteins provide phosphatidylethanolamine for GPI anchor synthesis in the ER.",
                "URL": null,
                "raw_pages": "e202111095",
                "medline_journal": "J Cell Biol",
                "ISO_journal": "J Cell Biol",
                "authors": [
                    "Toulmay A",
                    "Whittle FB",
                    "Yang J",
                    "Bai X",
                    "Diarra J",
                    "Banerjee S",
                    "Levine TP",
                    "Golden A",
                    "Prinz WA."
                ],
                "DOI_URL": null
            },
            "PUB00070565": {
                "PMID": 10781556,
                "ISBN": null,
                "volume": "182",
                "issue": "10",
                "year": 2000,
                "title": "Cloning and characterization of the CSF1 gene of Saccharomyces cerevisiae, which is required for nutrient uptake at low temperature.",
                "URL": null,
                "raw_pages": "2865-8",
                "medline_journal": "J Bacteriol",
                "ISO_journal": "J. Bacteriol.",
                "authors": [
                    "Tokai M",
                    "Kawasaki H",
                    "Kikuchi Y",
                    "Ouchi K."
                ],
                "DOI_URL": "http://dx.doi.org/10.1128/JB.182.10.2865-2868.2000"
            }
        },
        "set_info": null,
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 28,
            "interactions": 0,
            "matches": 1539,
            "pathways": 0,
            "proteins": 1304,
            "proteomes": 1041,
            "sets": 0,
            "structural_models": {
                "alphafold": 37,
                "bfvd": 0
            },
            "structures": 0,
            "taxa": 2186
        },
        "entry_annotations": {
            "alignment:seed": 2,
            "alignment:full": 1016
        },
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}