General Handler

HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept

{
    "metadata": {
        "accession": "IPR053585",
        "entry_id": null,
        "type": "family",
        "go_terms": null,
        "source_database": "interpro",
        "member_databases": {
            "ncbifam": {
                "NF042423": "3-beta-Hydroxysteroid Dehydrogenase-like"
            }
        },
        "integrated": null,
        "hierarchy": {
            "accession": "IPR053585",
            "name": "3-beta-Hydroxysteroid Dehydrogenase-like",
            "type": "Family",
            "children": []
        },
        "name": {
            "name": "3-beta-Hydroxysteroid Dehydrogenase-like",
            "short": "3-beta-HSD-like"
        },
        "description": [
            {
                "text": "<p>This family of proteins is involved in the biosynthesis of olefins, a class of hydrocarbons. Members of this family function as enzymes that catalyze the NADPH-dependent reduction of 2-alkyl-3-oxoalkanoic acids to their corresponding 2-alkyl-3-hydroxyalkanoic acids. This reaction is reversible and stereospecific. The enzymatic activity is crucial for the production of certain olefins, such as 3,6,9,12,15,19,22,25,28-hentriacontanonaene, which may play a role in cellular adaptation to environmental changes, such as temperature fluctuations.</p>",
                "llm": true,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00153446": {
                "PMID": 20418444,
                "ISBN": null,
                "volume": "76",
                "issue": "12",
                "year": 2010,
                "title": "Structure, function, and insights into the biosynthesis of a head-to-head hydrocarbon in Shewanella oneidensis strain MR-1.",
                "URL": null,
                "raw_pages": "3842-9",
                "medline_journal": "Appl Environ Microbiol",
                "ISO_journal": "Appl Environ Microbiol",
                "authors": [
                    "Sukovich DJ",
                    "Seffernick JL",
                    "Richman JE",
                    "Hunt KA",
                    "Gralnick JA",
                    "Wackett LP."
                ],
                "DOI_URL": "https://doi.org/10.1128/AEM.00433-10"
            }
        },
        "set_info": null,
        "overlaps_with": [
            {
                "accession": "IPR036291",
                "name": "NAD(P)-binding domain superfamily",
                "type": "homologous_superfamily"
            }
        ],
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 0,
            "interactions": 0,
            "matches": 112,
            "pathways": 0,
            "proteins": 112,
            "proteomes": 88,
            "sets": 0,
            "structural_models": {
                "alphafold": 69,
                "bfvd": 0
            },
            "structures": 0,
            "taxa": 136
        },
        "entry_annotations": {},
        "cross_references": {},
        "is_llm": true,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}