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InterPro-Version: 108.0
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{
    "metadata": {
        "accession": "IPR052036",
        "entry_id": null,
        "type": "family",
        "go_terms": null,
        "source_database": "interpro",
        "member_databases": {
            "panther": {
                "PTHR31299": "Hydrolase/Phosphoribosyltransferase-associated"
            }
        },
        "integrated": null,
        "hierarchy": {
            "accession": "IPR052036",
            "name": "Hydrolase/Phosphoribosyltransferase-associated",
            "type": "Family",
            "children": []
        },
        "name": {
            "name": "Hydrolase/Phosphoribosyltransferase-associated",
            "short": "Hydrolase/PRTase-associated"
        },
        "description": [
            {
                "text": "<p>This family of proteins includes enzymes with diverse hydrolytic activities. Some members are involved in the hydrolysis of the lactone ring of erythromycin, conferring resistance to this antibiotic. Other members are predicted to have phosphoribosyltransferase activity, which is typically associated with the synthesis of nucleotide precursors by transferring a phosphoribosyl group to purine or pyrimidine bases. The family appears to be functionally diverse, with some proteins containing domains indicative of a role in dienelactone hydrolase activity, which is involved in the breakdown of dienelactone, a compound related to environmental aromatic pollutants.</p>",
                "llm": true,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": null,
        "set_info": null,
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 0,
            "interactions": 0,
            "matches": 8833,
            "pathways": 0,
            "proteins": 8833,
            "proteomes": 4597,
            "sets": 0,
            "structural_models": {
                "alphafold": 6106,
                "bfvd": 0
            },
            "structures": 5,
            "taxa": 7638
        },
        "entry_annotations": {},
        "cross_references": {},
        "is_llm": true,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": {
            "accession": "2qgm",
            "name": "Crystal structure of succinoglycan biosynthesis protein at the resolution 1.7 A. Northeast Structural Genomics Consortium target BcR136."
        }
    }
}