GET /api/entry/InterPro/IPR052006/?format=api
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Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
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{
"metadata": {
"accession": "IPR052006",
"entry_id": null,
"type": "family",
"go_terms": null,
"source_database": "interpro",
"member_databases": {
"panther": {
"PTHR31338": "Major Latex-like"
}
},
"integrated": null,
"hierarchy": {
"accession": "IPR052006",
"name": "Major Latex-like",
"type": "Family",
"children": []
},
"name": {
"name": "Major Latex-like",
"short": "MLP-like"
},
"description": [
{
"text": "<p>This family of proteins includes members with a yet undefined role, which are known to be abundant in latex, constituting a significant portion of its soluble protein content. Some members of this family have been characterized to catalyze the formation of thebaine from its precursors, indicating a role in alkaloid biosynthesis. These enzymes function by facilitating the conversion of (7S)-salutaridinol 7-O-acetate into thebaine while minimizing the production of hydroxylated by-products through spontaneous allylic elimination. The activity of these enzymes can be slightly inhibited by certain substrates, suggesting a regulatory mechanism in the biosynthetic pathway. The diverse functions within this family reflect a range of biological roles, from enzymatic activity in secondary metabolism to yet-to-be-determined functions in plant physiology.</p>",
"llm": true,
"checked": false,
"updated": false
}
],
"wikipedia": null,
"literature": null,
"set_info": null,
"overlaps_with": [
{
"accession": "IPR023393",
"name": "START-like domain superfamily",
"type": "homologous_superfamily"
}
],
"counters": {
"subfamilies": 0,
"domain_architectures": 0,
"interactions": 0,
"matches": 2480,
"pathways": 0,
"proteins": 2480,
"proteomes": 222,
"sets": 0,
"structural_models": {
"alphafold": 2135,
"bfvd": 0
},
"structures": 9,
"taxa": 665
},
"entry_annotations": {},
"cross_references": {},
"is_llm": true,
"is_reviewed_llm": false,
"is_updated_llm": false,
"representative_structure": {
"accession": "8vo1",
"name": "Pathogenesis related 10-10 C155S mutant"
}
}
}