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{
    "metadata": {
        "accession": "IPR051573",
        "entry_id": null,
        "type": "family",
        "go_terms": null,
        "source_database": "interpro",
        "member_databases": {
            "panther": {
                "PTHR24136": "Ankyrin repeat and SOCS box domain-containing protein"
            }
        },
        "integrated": null,
        "hierarchy": {
            "accession": "IPR051573",
            "name": "Ankyrin repeat and SOCS box protein-like",
            "type": "Family",
            "children": []
        },
        "name": {
            "name": "Ankyrin repeat and SOCS box protein-like",
            "short": "Ankyrin-SOCS_box_domain"
        },
        "description": [
            {
                "text": "<p>This family of proteins includes components that may act as substrate-recognition modules within SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complexes. These complexes are involved in the ubiquitination and subsequent proteasomal degradation of target proteins, which is a critical process in regulating various cellular functions. Some members of this family are implicated in the initiation of arteriogenesis. The presence of ankyrin repeats suggests a role in protein-protein interactions, while the SOCS box domain is essential for binding to the Elongin BC complex, which is a part of the E3 ubiquitin ligase complex.</p>",
                "llm": true,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": null,
        "set_info": null,
        "overlaps_with": [
            {
                "accession": "IPR036770",
                "name": "Ankyrin repeat-containing domain superfamily",
                "type": "homologous_superfamily"
            }
        ],
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 0,
            "interactions": 0,
            "matches": 7885,
            "pathways": 8,
            "proteins": 7885,
            "proteomes": 1581,
            "sets": 0,
            "structural_models": {
                "alphafold": 7188,
                "bfvd": 2
            },
            "structures": 5,
            "taxa": 5417
        },
        "entry_annotations": {},
        "cross_references": {},
        "is_llm": true,
        "is_reviewed_llm": true,
        "is_updated_llm": true,
        "representative_structure": {
            "accession": "4uuc",
            "name": "Crystal structure of human ASB11 ankyrin repeat domain"
        }
    }
}