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{
    "metadata": {
        "accession": "IPR050312",
        "entry_id": null,
        "type": "family",
        "go_terms": null,
        "source_database": "interpro",
        "member_databases": {
            "panther": {
                "PTHR12110": "Inositol Catabolism and Carbohydrate Metabolism"
            }
        },
        "integrated": null,
        "hierarchy": {
            "accession": "IPR050312",
            "name": "IolE/XylA/MocC-like",
            "type": "Family",
            "children": [
                {
                    "accession": "IPR030823",
                    "name": "IolE/MocC family",
                    "type": "Family",
                    "children": [
                        {
                            "accession": "IPR023952",
                            "name": "Inosose dehydratase",
                            "type": "Family",
                            "children": []
                        }
                    ]
                },
                {
                    "accession": "IPR043700",
                    "name": "3-dehydroshikimate dehydratase",
                    "type": "Family",
                    "children": [
                        {
                            "accession": "IPR050009",
                            "name": "3-dehydroshikimate dehydratase QuiC",
                            "type": "Family",
                            "children": []
                        }
                    ]
                }
            ]
        },
        "name": {
            "name": "IolE/XylA/MocC-like",
            "short": "IolE/XylAMocC-like"
        },
        "description": [
            {
                "text": "<p>The IolE/XylA/MocC family proteins are primarily involved in the metabolism of inositol and its derivatives. They catalyse the dehydration of inosose to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione, a key step in the catabolism of inositol. Inosose dehydratases from this family convert 2-keto-myo-inositol to D-2,3-diketo-4-deoxy-epi-inositol. Additionally, some members are implicated in the reversible interconversion of 2-keto-myo-inositol to 1-keto-D-chiro-inositol. The family also includes proteins involved in the catabolism of rhizopine, xylose, and other sugars, highlighting a broader role in carbohydrate metabolism. The enzymes exhibit a diverse range of substrate specificities and activities, including epimerisation of ketoses and dehydration reactions, contributing to various metabolic pathways across different organisms.</p>",
                "llm": true,
                "checked": true,
                "updated": true
            }
        ],
        "wikipedia": null,
        "literature": null,
        "set_info": null,
        "overlaps_with": [
            {
                "accession": "IPR036237",
                "name": "Xylose isomerase-like superfamily",
                "type": "homologous_superfamily"
            }
        ],
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 0,
            "interactions": 0,
            "matches": 90574,
            "pathways": 0,
            "proteins": 90574,
            "proteomes": 13096,
            "sets": 0,
            "structural_models": {
                "alphafold": 64995,
                "bfvd": 1
            },
            "structures": 89,
            "taxa": 21795
        },
        "entry_annotations": {},
        "cross_references": {},
        "is_llm": true,
        "is_reviewed_llm": true,
        "is_updated_llm": true,
        "representative_structure": {
            "accession": "3qc0",
            "name": "Crystal structure of a sugar isomerase (SMc04130) from SINORHIZOBIUM MELILOTI 1021 at 1.45 A resolution"
        }
    }
}