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{
"metadata": {
"accession": "IPR050194",
"entry_id": null,
"type": "family",
"go_terms": null,
"source_database": "interpro",
"member_databases": {
"panther": {
"PTHR45947": "Glycosyltransferase group 1"
}
},
"integrated": null,
"hierarchy": {
"accession": "IPR050194",
"name": "Glycosyltransferase group 1",
"type": "Family",
"children": []
},
"name": {
"name": "Glycosyltransferase group 1",
"short": "Glycosyltransferase_grp1"
},
"description": [
{
"text": "<p>The glycosyltransferase group 1 family is involved in various biosynthetic pathways across different organisms, catalyzing the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Members of this family play crucial roles in the synthesis of important biological molecules such as mycothiol, a major redox buffer protecting bacteria against oxidative stress and antibiotics, and capsular polysaccharides, which are essential for bacterial virulence and biofilm formation. They are also involved in the production of lipopolysaccharides and exopolysaccharides, contributing to bacterial pathogenicity and environmental adaptability. Additionally, they participate in the biosynthesis of glycolipids and glycoproteins, impacting cell membrane structure and protein function.</p>",
"llm": true,
"checked": false,
"updated": false
}
],
"wikipedia": null,
"literature": null,
"set_info": null,
"overlaps_with": null,
"counters": {
"subfamilies": 0,
"domain_architectures": 0,
"interactions": 0,
"matches": 119892,
"pathways": 0,
"proteins": 119892,
"proteomes": 17702,
"sets": 0,
"structural_models": {
"alphafold": 89712,
"bfvd": 4
},
"structures": 27,
"taxa": 31844
},
"entry_annotations": {},
"cross_references": {
"ec": {
"displayName": "ENZYME",
"description": "ENZYME is a repository of information relative to the nomenclature of enzymes. It is primarily based on the recommendations of the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (IUBMB) and it describes each type of characterized enzyme for which an EC (Enzyme Commission) number has been provided.",
"rank": 19,
"accessions": [
{
"accession": "2.4.1",
"url": "https://enzyme.expasy.org/EC/2.4.1"
}
]
}
},
"is_llm": true,
"is_reviewed_llm": false,
"is_updated_llm": false,
"representative_structure": {
"accession": "5ze7",
"name": "UDP Glucose alpha tetrahydrobiopterin glycosyltransferase from Synechococcus species PCC 7942 - apo form"
}
}
}