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InterPro-Version: 108.0
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{
"metadata": {
"accession": "IPR049651",
"entry_id": null,
"type": "family",
"go_terms": null,
"source_database": "interpro",
"member_databases": {
"ncbifam": {
"NF041673": "acetate metabolism transcriptional regulator RamA"
}
},
"integrated": null,
"hierarchy": {
"accession": "IPR049651",
"name": "HTH-type transcriptional activator RamA-like",
"type": "Family",
"children": []
},
"name": {
"name": "HTH-type transcriptional activator RamA-like",
"short": "HTH-type_RamA-like"
},
"description": [
{
"text": "<p>This entry represents a group of proteins from actinomycetes, including HTH-type transcriptional activator RamA from Corynebacterium glutamicum ([swissprot:Q8NML3]), a master regulator of acetate metabolism. RamA positively controls the expression of acnA, aceA, aceB, ack, pta and ramB genes in the presence of acetate [[cite:PUB00152919], [cite:PUB00153071], [cite:PUB00152920]] and a positive regulator of rpf2 gene expression during growth on glucose as the sole carbon source [[cite:PUB00152921]].</p>",
"llm": false,
"checked": false,
"updated": false
}
],
"wikipedia": null,
"literature": {
"PUB00152919": {
"PMID": 16547043,
"ISBN": null,
"volume": "188",
"issue": "7",
"year": 2006,
"title": "Identification of RamA, a novel LuxR-type transcriptional regulator of genes involved in acetate metabolism of Corynebacterium glutamicum.",
"URL": null,
"raw_pages": "2554-67",
"medline_journal": "J Bacteriol",
"ISO_journal": "J Bacteriol",
"authors": [
"Cramer A",
"Gerstmeir R",
"Schaffer S",
"Bott M",
"Eikmanns BJ."
],
"DOI_URL": "https://doi.org/10.1128/JB.188.7.2554-2567.2006"
},
"PUB00152920": {
"PMID": 19095019,
"ISBN": null,
"volume": "140",
"issue": "1-2",
"year": 2009,
"title": "Complex expression control of the Corynebacterium glutamicum aconitase gene: identification of RamA as a third transcriptional regulator besides AcnR and RipA.",
"URL": null,
"raw_pages": "92-8",
"medline_journal": "J Biotechnol",
"ISO_journal": "J Biotechnol",
"authors": [
"Emer D",
"Krug A",
"Eikmanns BJ",
"Bott M."
],
"DOI_URL": "https://doi.org/10.1016/j.jbiotec.2008.11.003"
},
"PUB00152921": {
"PMID": 18355281,
"ISBN": null,
"volume": "281",
"issue": "2",
"year": 2008,
"title": "Triple transcriptional control of the resuscitation promoting factor 2 (rpf2) gene of Corynebacterium glutamicum by the regulators of acetate metabolism RamA and RamB and the cAMP-dependent regulator GlxR.",
"URL": null,
"raw_pages": "190-7",
"medline_journal": "FEMS Microbiol Lett",
"ISO_journal": "FEMS Microbiol Lett",
"authors": [
"Jungwirth B",
"Emer D",
"Brune I",
"Hansmeier N",
"Puhler A",
"Eikmanns BJ",
"Tauch A."
],
"DOI_URL": "https://doi.org/10.1111/j.1574-6968.2008.01098.x"
},
"PUB00153071": {
"PMID": 17114251,
"ISBN": null,
"volume": "189",
"issue": "3",
"year": 2007,
"title": "RamB, the transcriptional regulator of acetate metabolism in Corynebacterium glutamicum, is subject to regulation by RamA and RamB.",
"URL": null,
"raw_pages": "1145-9",
"medline_journal": "J Bacteriol",
"ISO_journal": "J Bacteriol",
"authors": [
"Cramer A",
"Auchter M",
"Frunzke J",
"Bott M",
"Eikmanns BJ."
],
"DOI_URL": "https://doi.org/10.1128/JB.01061-06"
}
},
"set_info": null,
"overlaps_with": null,
"counters": {
"subfamilies": 0,
"domain_architectures": 0,
"interactions": 0,
"matches": 204,
"pathways": 0,
"proteins": 204,
"proteomes": 153,
"sets": 0,
"structural_models": {
"alphafold": 163,
"bfvd": 0
},
"structures": 0,
"taxa": 215
},
"entry_annotations": {},
"cross_references": {},
"is_llm": false,
"is_reviewed_llm": false,
"is_updated_llm": false,
"representative_structure": null
}
}
