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InterPro-Version: 108.0
InterPro-Version-Minor: 0
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{
"metadata": {
"accession": "IPR044801",
"entry_id": null,
"type": "family",
"go_terms": [
{
"identifier": "GO:0051015",
"name": "actin filament binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0030036",
"name": "actin cytoskeleton organization",
"category": {
"code": "P",
"name": "biological_process"
}
}
],
"source_database": "interpro",
"member_databases": {
"panther": {
"PTHR38537": "JITTERBUG, ISOFORM N"
}
},
"integrated": null,
"hierarchy": {
"accession": "IPR044801",
"name": "Filamin family",
"type": "Family",
"children": []
},
"name": {
"name": "Filamin family",
"short": "Filamin"
},
"description": [
{
"text": "<p>Filamin family consists of Filamin-A (FLN-A), Filamin-B (FLN-B) and Filamin-C (FLN-C). They are a group of actin binding proteins that may be involved in actin microfilaments organisation [[cite:PUB00035297]].</p>",
"llm": false,
"checked": false,
"updated": false
},
{
"text": "<p>This entry also includes gelation factor AbpC from Dictyostelium discoideum [[cite:PUB00010567]] and protein GAMETE EXPRESSED 2 from Arabidopsis [[cite:PUB00097101]].</p>",
"llm": false,
"checked": false,
"updated": false
}
],
"wikipedia": null,
"literature": {
"PUB00035297": {
"PMID": 15516996,
"ISBN": null,
"volume": "6",
"issue": "11",
"year": 2004,
"title": "The many faces of filamin: a versatile molecular scaffold for cell motility and signalling.",
"URL": null,
"raw_pages": "1034-8",
"medline_journal": "Nat Cell Biol",
"ISO_journal": "Nat. Cell Biol.",
"authors": [
"Feng Y",
"Walsh CA."
],
"DOI_URL": "http://dx.doi.org/10.1038/ncb1104-1034"
},
"PUB00097101": {
"PMID": 24388850,
"ISBN": null,
"volume": "24",
"issue": "2",
"year": 2014,
"title": "Gamete attachment requires GEX2 for successful fertilization in Arabidopsis.",
"URL": null,
"raw_pages": "170-175",
"medline_journal": "Curr Biol",
"ISO_journal": "Curr Biol",
"authors": [
"Mori T",
"Igawa T",
"Tamiya G",
"Miyagishima SY",
"Berger F."
],
"DOI_URL": null
},
"PUB00010567": {
"PMID": 10467095,
"ISBN": null,
"volume": "6",
"issue": "9",
"year": 1999,
"title": "Structural basis for dimerization of the Dictyostelium gelation factor (ABP120) rod.",
"URL": null,
"raw_pages": "836-41",
"medline_journal": "Nat Struct Biol",
"ISO_journal": "Nat. Struct. Biol.",
"authors": [
"McCoy AJ",
"Fucini P",
"Noegel AA",
"Stewart M."
],
"DOI_URL": "http://dx.doi.org/10.1038/12296"
}
},
"set_info": null,
"overlaps_with": null,
"counters": {
"subfamilies": 0,
"domain_architectures": 0,
"interactions": 0,
"matches": 11723,
"pathways": 20,
"proteins": 11723,
"proteomes": 1562,
"sets": 0,
"structural_models": {
"alphafold": 4359,
"bfvd": 0
},
"structures": 70,
"taxa": 5533
},
"entry_annotations": {},
"cross_references": {},
"is_llm": false,
"is_reviewed_llm": false,
"is_updated_llm": false,
"representative_structure": {
"accession": "2w0p",
"name": "Crystal structure of the filamin A repeat 21 complexed with the migfilin peptide"
}
}
}
