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InterPro-Version: 108.0
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{
"metadata": {
"accession": "IPR044626",
"entry_id": null,
"type": "family",
"go_terms": [
{
"identifier": "GO:0016628",
"name": "oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor",
"category": {
"code": "F",
"name": "molecular_function"
}
}
],
"source_database": "interpro",
"member_databases": {
"panther": {
"PTHR44573": "NADPH-DEPENDENT ALKENAL/ONE OXIDOREDUCTASE, CHLOROPLASTIC"
}
},
"integrated": null,
"hierarchy": {
"accession": "IPR044626",
"name": "NADPH-dependent oxidoreductase AOR-like",
"type": "Family",
"children": []
},
"name": {
"name": "NADPH-dependent oxidoreductase AOR-like",
"short": "AOR-like"
},
"description": [
{
"text": "<p>This entry represents a group of plant NADPH-dependent oxidoreductases, including FaQR from Fragaria ananassa and AOR from Arabidopsis thaliana. FaQR is an enone oxidoreductase involved in the biosynthesis of 4-hydroxy-2,5-dimethyl-3(2H)-furanone (HDMF or furaneol), the key flavour compound in strawberries [[cite:PUB00096558]]. AOR is a NADPH-dependent reductase involved in the detoxification of reactive carbonyls [[cite:PUB00096559], [cite:PUB00096560]].</p>",
"llm": false,
"checked": false,
"updated": false
}
],
"wikipedia": null,
"literature": {
"PUB00096558": {
"PMID": 16517758,
"ISBN": null,
"volume": "18",
"issue": "4",
"year": 2006,
"title": "FaQR, required for the biosynthesis of the strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone, encodes an enone oxidoreductase.",
"URL": null,
"raw_pages": "1023-37",
"medline_journal": "Plant Cell",
"ISO_journal": "Plant Cell",
"authors": [
"Raab T",
"Lopez-Raez JA",
"Klein D",
"Caballero JL",
"Moyano E",
"Schwab W",
"Munoz-Blanco J."
],
"DOI_URL": null
},
"PUB00096559": {
"PMID": 21169366,
"ISBN": null,
"volume": "286",
"issue": "9",
"year": 2011,
"title": "NADPH-dependent reductases involved in the detoxification of reactive carbonyls in plants.",
"URL": null,
"raw_pages": "6999-7009",
"medline_journal": "J Biol Chem",
"ISO_journal": "J. Biol. Chem.",
"authors": [
"Yamauchi Y",
"Hasegawa A",
"Taninaka A",
"Mizutani M",
"Sugimoto Y."
],
"DOI_URL": null
},
"PUB00096560": {
"PMID": 22575657,
"ISBN": null,
"volume": "586",
"issue": "8",
"year": 2012,
"title": "Chloroplastic NADPH-dependent alkenal/one oxidoreductase contributes to the detoxification of reactive carbonyls produced under oxidative stress.",
"URL": null,
"raw_pages": "1208-13",
"medline_journal": "FEBS Lett",
"ISO_journal": "FEBS Lett.",
"authors": [
"Yamauchi Y",
"Hasegawa A",
"Mizutani M",
"Sugimoto Y."
],
"DOI_URL": null
}
},
"set_info": null,
"overlaps_with": null,
"counters": {
"subfamilies": 0,
"domain_architectures": 0,
"interactions": 0,
"matches": 1913,
"pathways": 2,
"proteins": 1913,
"proteomes": 437,
"sets": 0,
"structural_models": {
"alphafold": 1650,
"bfvd": 0
},
"structures": 6,
"taxa": 1458
},
"entry_annotations": {},
"cross_references": {
"ec": {
"displayName": "ENZYME",
"description": "ENZYME is a repository of information relative to the nomenclature of enzymes. It is primarily based on the recommendations of the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (IUBMB) and it describes each type of characterized enzyme for which an EC (Enzyme Commission) number has been provided.",
"rank": 19,
"accessions": [
{
"accession": "1.3.1.105",
"url": "https://enzyme.expasy.org/EC/1.3.1.105"
}
]
}
},
"is_llm": false,
"is_reviewed_llm": false,
"is_updated_llm": false,
"representative_structure": {
"accession": "4idc",
"name": "Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADPH and HDMF"
}
}
}
