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{
    "metadata": {
        "accession": "IPR042619",
        "entry_id": null,
        "type": "family",
        "go_terms": [
            {
                "identifier": "GO:0051131",
                "name": "chaperone-mediated protein complex assembly",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "source_database": "interpro",
        "member_databases": {
            "panther": {
                "PTHR14667": "BARDET-BIEDL SYNDROME 10 PROTEIN"
            }
        },
        "integrated": null,
        "hierarchy": {
            "accession": "IPR042619",
            "name": "BBSome complex assembly protein BBS10",
            "type": "Family",
            "children": []
        },
        "name": {
            "name": "BBSome complex assembly protein BBS10",
            "short": "BBS10"
        },
        "description": [
            {
                "text": "<p>Bardet-Biedl syndrome (BBS) is a human genetic disorder associated with ciliary dysfunction, resulting in obesity, retinal degeneration, polydactyly, and nephropathy. Twelve BBS genes (BBS1-12) have been identified. BBS6, BBS10, and BBS12 have sequence homology to the CCT (also known as TRiC) family of group II chaperonins. They form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly [[cite:PUB00069285]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00069285": {
                "PMID": 20080638,
                "ISBN": null,
                "volume": "107",
                "issue": "4",
                "year": 2010,
                "title": "BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly.",
                "URL": null,
                "raw_pages": "1488-93",
                "medline_journal": "Proc Natl Acad Sci U S A",
                "ISO_journal": "Proc. Natl. Acad. Sci. U.S.A.",
                "authors": [
                    "Seo S",
                    "Baye LM",
                    "Schulz NP",
                    "Beck JS",
                    "Zhang Q",
                    "Slusarski DC",
                    "Sheffield VC."
                ],
                "DOI_URL": "http://dx.doi.org/10.1073/pnas.0910268107"
            }
        },
        "set_info": null,
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 0,
            "interactions": 0,
            "matches": 1071,
            "pathways": 1,
            "proteins": 1071,
            "proteomes": 795,
            "sets": 0,
            "structural_models": {
                "alphafold": 978,
                "bfvd": 0
            },
            "structures": 0,
            "taxa": 2712
        },
        "entry_annotations": {},
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}