General Handler

HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 107.0
InterPro-Version-Minor: 0
Vary: Accept

{
    "metadata": {
        "accession": "IPR040028",
        "entry_id": null,
        "type": "family",
        "go_terms": null,
        "source_database": "interpro",
        "member_databases": {
            "pfam": {
                "PF17722": "Intraflagellar transport-associated protein"
            },
            "panther": {
                "PTHR35543": "PROTEIN C11ORF74"
            }
        },
        "integrated": null,
        "hierarchy": {
            "accession": "IPR040028",
            "name": "Intraflagellar transport-associated protein",
            "type": "Family",
            "children": []
        },
        "name": {
            "name": "Intraflagellar transport-associated protein",
            "short": "IFTAP"
        },
        "description": [
            {
                "text": "<p>IFTAP (C11ORF74) interacts with the IFT-A complex and is accumulated at the distal tip in the absence of an IFT-A subunit IFT139. In IFTAP-knockout (KO) cells, the BBSome components cannot enter cilia. However, IFTAP-KO mice demonstrated no obvious anatomical abnormalities associated with ciliary dysfunctions [[cite:PUB00093954]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00093954": {
                "PMID": 30476139,
                "ISBN": null,
                "volume": "165",
                "issue": "3",
                "year": 2019,
                "title": "C11ORF74 interacts with the IFT-A complex and participates in ciliary BBSome localization.",
                "URL": null,
                "raw_pages": "257-267",
                "medline_journal": "J Biochem",
                "ISO_journal": "J. Biochem.",
                "authors": [
                    "Takahara M",
                    "Kunii M",
                    "Nakamura K",
                    "Harada A",
                    "Hirano T",
                    "Katoh Y",
                    "Nakayama K."
                ],
                "DOI_URL": null
            }
        },
        "set_info": null,
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 5,
            "interactions": 0,
            "matches": 680,
            "pathways": 0,
            "proteins": 652,
            "proteomes": 340,
            "sets": 0,
            "structural_models": {
                "alphafold": 601,
                "bfvd": 0
            },
            "structures": 0,
            "taxa": 1210
        },
        "entry_annotations": {
            "alignment:seed": 10,
            "alignment:full": 622
        },
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}