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{
    "metadata": {
        "accession": "IPR036169",
        "entry_id": null,
        "type": "homologous_superfamily",
        "go_terms": null,
        "source_database": "interpro",
        "member_databases": {
            "ssf": {
                "SSF69055": "1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain"
            }
        },
        "integrated": null,
        "hierarchy": {
            "accession": "IPR036169",
            "name": "DXP reductoisomerase, C-terminal domain superfamily",
            "type": "Homologous_superfamily",
            "children": []
        },
        "name": {
            "name": "DXP reductoisomerase, C-terminal domain superfamily",
            "short": "DXPR_C_sf"
        },
        "description": [
            {
                "text": "<p>This entry represents the C-terminal domain of the 1-deoxy-D-xylulose-5-phosphate reductoisomerase enzymes. This domain forms a left handed super-helix. DXP reductoisomerase catalyses the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) [[cite:PUB00016120]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00016120": {
                "PMID": 10787409,
                "ISBN": null,
                "volume": "275",
                "issue": "26",
                "year": 2000,
                "title": "Characterization of 1-deoxy-D-xylulose 5-phosphate reductoisomerase, an enzyme involved in isopentenyl diphosphate biosynthesis, and identification of its catalytic amino acid residues.",
                "URL": null,
                "raw_pages": "19928-32",
                "medline_journal": "J Biol Chem",
                "ISO_journal": "J. Biol. Chem.",
                "authors": [
                    "Kuzuyama T",
                    "Takahashi S",
                    "Takagi M",
                    "Seto H."
                ],
                "DOI_URL": "http://dx.doi.org/10.1074/jbc.M001820200"
            }
        },
        "set_info": null,
        "overlaps_with": [
            {
                "accession": "IPR026877",
                "name": "DXP reductoisomerase, C-terminal domain",
                "type": "domain"
            },
            {
                "accession": "IPR003821",
                "name": "1-deoxy-D-xylulose 5-phosphate reductoisomerase",
                "type": "family"
            }
        ],
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 0,
            "interactions": 0,
            "matches": 22999,
            "pathways": 1,
            "proteins": 22986,
            "proteomes": 14797,
            "sets": 0,
            "structural_models": {
                "alphafold": 17828,
                "bfvd": 0
            },
            "structures": 88,
            "taxa": 25416
        },
        "entry_annotations": {},
        "cross_references": {
            "ec": {
                "displayName": "ENZYME",
                "description": "ENZYME is a repository of information relative to the nomenclature of enzymes. It is primarily based on the recommendations of the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (IUBMB) and it describes each type of characterized enzyme for which an EC (Enzyme Commission) number has been provided.",
                "rank": 19,
                "accessions": [
                    {
                        "accession": "1.1.1.267",
                        "url": "https://enzyme.expasy.org/EC/1.1.1.267"
                    }
                ]
            }
        },
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}