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InterPro-Version: 108.0
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{
"metadata": {
"accession": "IPR032402",
"entry_id": null,
"type": "domain",
"go_terms": null,
"source_database": "interpro",
"member_databases": {
"pfam": {
"PF16182": "Putative adherens-junction anchoring region of AbLIM"
}
},
"integrated": null,
"hierarchy": {
"accession": "IPR032402",
"name": "Putative adherens-junction anchoring domain",
"type": "Domain",
"children": []
},
"name": {
"name": "Putative adherens-junction anchoring domain",
"short": "AbLIM_anchor"
},
"description": [
{
"text": "<p>This is a domain lying between the LIM actin-binding and the vilin-head domains of actin-binding LIM proteins (abLIMs). It is likely that this domain is involved in anchoring abLIMs to circumferential actin bundles in specific cell types [[cite:PUB00076303]]. It is also found in Dematin, an actin-binding protein originally identified in the junctional complex of the erythrocyte plasma membrane [[cite:PUB00076305]].</p>",
"llm": false,
"checked": false,
"updated": false
}
],
"wikipedia": null,
"literature": {
"PUB00076303": {
"PMID": 20709423,
"ISBN": null,
"volume": "89",
"issue": "11",
"year": 2010,
"title": "abLIM3 is a novel component of adherens junctions with actin-binding activity.",
"URL": null,
"raw_pages": "807-16",
"medline_journal": "Eur J Cell Biol",
"ISO_journal": "Eur. J. Cell Biol.",
"authors": [
"Matsuda M",
"Yamashita JK",
"Tsukita S",
"Furuse M."
],
"DOI_URL": "http://dx.doi.org/10.1016/j.ejcb.2010.07.009"
},
"PUB00076305": {
"PMID": 19241372,
"ISBN": null,
"volume": "18",
"issue": "3",
"year": 2009,
"title": "Dematin exhibits a natively unfolded core domain and an independently folded headpiece domain.",
"URL": null,
"raw_pages": "629-36",
"medline_journal": "Protein Sci",
"ISO_journal": "Protein Sci.",
"authors": [
"Chen L",
"Jiang ZG",
"Khan AA",
"Chishti AH",
"McKnight CJ."
],
"DOI_URL": "http://dx.doi.org/10.1002/pro.59"
}
},
"set_info": null,
"overlaps_with": null,
"counters": {
"subfamilies": 0,
"domain_architectures": 61,
"interactions": 0,
"matches": 13422,
"pathways": 4,
"proteins": 10347,
"proteomes": 846,
"sets": 0,
"structural_models": {
"alphafold": 9408,
"bfvd": 0
},
"structures": 4,
"taxa": 2917
},
"entry_annotations": {
"alignment:seed": 20,
"alignment:full": 11185
},
"cross_references": {},
"is_llm": false,
"is_reviewed_llm": false,
"is_updated_llm": false,
"representative_structure": null
}
}