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{
    "metadata": {
        "accession": "IPR026596",
        "entry_id": null,
        "type": "family",
        "go_terms": null,
        "source_database": "interpro",
        "member_databases": {
            "hamap": {
                "MF_01520": "Bifunctional enzyme IspD/IspF [ispDF]"
            }
        },
        "integrated": null,
        "hierarchy": {
            "accession": "IPR026596",
            "name": "Bifunctional enzyme IspD/IspF",
            "type": "Family",
            "children": []
        },
        "name": {
            "name": "Bifunctional enzyme IspD/IspF",
            "short": "IspD/F"
        },
        "description": [
            {
                "text": "<p>This entry represents bifunctional enzyme that catalyses the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and converts 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MECDP) and CMP (IspF) [[cite:PUB00056865]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00056865": {
                "PMID": 15233799,
                "ISBN": null,
                "volume": "271",
                "issue": "14",
                "year": 2004,
                "title": "Biosynthesis of isoprenoids: a bifunctional IspDF enzyme from Campylobacter jejuni.",
                "URL": null,
                "raw_pages": "3028-35",
                "medline_journal": "Eur J Biochem",
                "ISO_journal": "Eur. J. Biochem.",
                "authors": [
                    "Gabrielsen M",
                    "Rohdich F",
                    "Eisenreich W",
                    "Grawert T",
                    "Hecht S",
                    "Bacher A",
                    "Hunter WN."
                ],
                "DOI_URL": "http://dx.doi.org/10.1111/j.1432-1033.2004.04234.x"
            }
        },
        "set_info": null,
        "overlaps_with": [
            {
                "accession": "IPR029044",
                "name": "Nucleotide-diphospho-sugar transferases",
                "type": "homologous_superfamily"
            }
        ],
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 0,
            "interactions": 0,
            "matches": 4352,
            "pathways": 1,
            "proteins": 4352,
            "proteomes": 3171,
            "sets": 0,
            "structural_models": {
                "alphafold": 3344,
                "bfvd": 0
            },
            "structures": 4,
            "taxa": 5196
        },
        "entry_annotations": {},
        "cross_references": {
            "ec": {
                "displayName": "ENZYME",
                "description": "ENZYME is a repository of information relative to the nomenclature of enzymes. It is primarily based on the recommendations of the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (IUBMB) and it describes each type of characterized enzyme for which an EC (Enzyme Commission) number has been provided.",
                "rank": 19,
                "accessions": [
                    {
                        "accession": "2.7.7.60",
                        "url": "https://enzyme.expasy.org/EC/2.7.7.60"
                    },
                    {
                        "accession": "4.6.1.12",
                        "url": "https://enzyme.expasy.org/EC/4.6.1.12"
                    }
                ]
            }
        },
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}