General Handler

HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept

{
    "metadata": {
        "accession": "IPR025972",
        "entry_id": null,
        "type": "domain",
        "go_terms": null,
        "source_database": "interpro",
        "member_databases": {
            "pfam": {
                "PF13363": "Beta-galactosidase, domain 3"
            }
        },
        "integrated": null,
        "hierarchy": {
            "accession": "IPR025972",
            "name": "Beta-galactosidase, domain 3",
            "type": "Domain",
            "children": []
        },
        "name": {
            "name": "Beta-galactosidase, domain 3",
            "short": "BetaGal_dom3"
        },
        "description": [
            {
                "text": "<p>This is the third domain of the five-domain beta-galactosidase enzyme that altogether catalyses the hydrolysis of beta(1-3) and beta(1-4) galactosyl bonds in oligosaccharides, as well as the inverse reaction of enzymatic condensation and trans-glycosylation. This domain has an Ig-like fold [[cite:PUB00031444]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00031444": {
                "PMID": 15491613,
                "ISBN": null,
                "volume": "343",
                "issue": "5",
                "year": 2004,
                "title": "Crystal structures of beta-galactosidase from Penicillium sp. and its complex with galactose.",
                "URL": null,
                "raw_pages": "1281-92",
                "medline_journal": "J Mol Biol",
                "ISO_journal": "J. Mol. Biol.",
                "authors": [
                    "Rojas AL",
                    "Nagem RA",
                    "Neustroev KN",
                    "Arand M",
                    "Adamska M",
                    "Eneyskaya EV",
                    "Kulminskaya AA",
                    "Garratt RC",
                    "Golubev AM",
                    "Polikarpov I."
                ],
                "DOI_URL": "http://dx.doi.org/10.1016/j.jmb.2004.09.012"
            }
        },
        "set_info": null,
        "overlaps_with": [
            {
                "accession": "IPR036833",
                "name": "Beta-galactosidase, domain 3 superfamily",
                "type": "homologous_superfamily"
            }
        ],
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 107,
            "interactions": 0,
            "matches": 4236,
            "pathways": 1,
            "proteins": 4234,
            "proteomes": 1510,
            "sets": 0,
            "structural_models": {
                "alphafold": 3328,
                "bfvd": 0
            },
            "structures": 13,
            "taxa": 2905
        },
        "entry_annotations": {
            "alignment:seed": 97,
            "alignment:full": 2703
        },
        "cross_references": {
            "ec": {
                "displayName": "ENZYME",
                "description": "ENZYME is a repository of information relative to the nomenclature of enzymes. It is primarily based on the recommendations of the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (IUBMB) and it describes each type of characterized enzyme for which an EC (Enzyme Commission) number has been provided.",
                "rank": 19,
                "accessions": [
                    {
                        "accession": "3.2.1.23",
                        "url": "https://enzyme.expasy.org/EC/3.2.1.23"
                    }
                ]
            }
        },
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}