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{
    "metadata": {
        "accession": "IPR022923",
        "entry_id": null,
        "type": "family",
        "go_terms": [
            {
                "identifier": "GO:0160104",
                "name": "tRNA (guanine(26)-N2)-dimethyltransferase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "source_database": "interpro",
        "member_databases": {
            "hamap": {
                "MF_00290": "tRNA (guanine(26)-N(2))-dimethyltransferase [trm1]"
            }
        },
        "integrated": null,
        "hierarchy": {
            "accession": "IPR002905",
            "name": "tRNA methyltransferase, Trm1",
            "type": "Family",
            "children": [
                {
                    "accession": "IPR022923",
                    "name": "tRNA (guanine(26)-N(2))-dimethyltransferase, archaeal and bacterial",
                    "type": "Family",
                    "children": []
                }
            ]
        },
        "name": {
            "name": "tRNA (guanine(26)-N(2))-dimethyltransferase, archaeal and bacterial",
            "short": "TRM1_arc_bac"
        },
        "description": [
            {
                "text": "<p>This entry represents tRNA (guanine(26)-N(2))-dimethyltransferase from archaea and bacteria.</p>\r\n\r\n<p>tRNA (guanine(26)-N(2))-dimethyltransferase  [ec:2.1.1.32] uses S-adenosyl-L-methionine to methylate tRNA.</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": null,
        "set_info": null,
        "overlaps_with": [
            {
                "accession": "IPR029063",
                "name": "S-adenosyl-L-methionine-dependent methyltransferase superfamily",
                "type": "homologous_superfamily"
            }
        ],
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 0,
            "interactions": 0,
            "matches": 708,
            "pathways": 1,
            "proteins": 708,
            "proteomes": 513,
            "sets": 0,
            "structural_models": {
                "alphafold": 675,
                "bfvd": 0
            },
            "structures": 6,
            "taxa": 1008
        },
        "entry_annotations": {},
        "cross_references": {
            "ec": {
                "displayName": "ENZYME",
                "description": "ENZYME is a repository of information relative to the nomenclature of enzymes. It is primarily based on the recommendations of the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (IUBMB) and it describes each type of characterized enzyme for which an EC (Enzyme Commission) number has been provided.",
                "rank": 19,
                "accessions": [
                    {
                        "accession": "2.1.1.216",
                        "url": "https://enzyme.expasy.org/EC/2.1.1.216"
                    }
                ]
            }
        },
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": {
            "accession": "2dul",
            "name": "Crystal structure of tRNA G26 methyltransferase Trm1 in apo form from Pyrococcus horikoshii"
        }
    }
}