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InterPro-Version: 108.0
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{
"metadata": {
"accession": "IPR020549",
"entry_id": null,
"type": "conserved_site",
"go_terms": null,
"source_database": "interpro",
"member_databases": {
"prosite": {
"PS01306": "Uncharacterized protein family UPF0054 signature"
}
},
"integrated": null,
"hierarchy": {
"accession": "IPR020549",
"name": "Endoribonuclease YbeY, conserved site",
"type": "Conserved_site",
"children": []
},
"name": {
"name": "Endoribonuclease YbeY, conserved site",
"short": "YbeY_CS"
},
"description": [
{
"text": "<p>YbeY is a single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. It acts together with the RNase R to eliminate defective 70S ribosomes, but not properly matured 70S ribosomes or individual subunits, by a process mediated specifically by the 30S ribosomal subunit. It is involved in the processing of 16S, 23S and 5S rRNAs, with a particularly strong effect on maturation at both the 5'-and 3'-ends of 16S rRNA as well as maturation of the 5'-end of 23S and 5S rRNAs [[cite:PUB00064741], [cite:PUB00064742], [cite:PUB00064743], [cite:PUB00038326]].</p>\r\n\r\n<p>YbeY contains a conserved region with three histidines at the C terminus. This entry represents this region.</p>",
"llm": false,
"checked": false,
"updated": false
}
],
"wikipedia": null,
"literature": {
"PUB00064741": {
"PMID": 20639334,
"ISBN": null,
"volume": "192",
"issue": "18",
"year": 2010,
"title": "The heat shock protein YbeY is required for optimal activity of the 30S ribosomal subunit.",
"URL": null,
"raw_pages": "4592-6",
"medline_journal": "J Bacteriol",
"ISO_journal": "J. Bacteriol.",
"authors": [
"Rasouly A",
"Davidovich C",
"Ron EZ."
],
"DOI_URL": "http://dx.doi.org/10.1128/JB.00448-10"
},
"PUB00064742": {
"PMID": 20807199,
"ISBN": null,
"volume": "78",
"issue": "2",
"year": 2010,
"title": "Role of Escherichia coli YbeY, a highly conserved protein, in rRNA processing.",
"URL": null,
"raw_pages": "506-18",
"medline_journal": "Mol Microbiol",
"ISO_journal": "Mol. Microbiol.",
"authors": [
"Davies BW",
"Kohrer C",
"Jacob AI",
"Simmons LA",
"Zhu J",
"Aleman LM",
"Rajbhandary UL",
"Walker GC."
],
"DOI_URL": "http://dx.doi.org/10.1111/j.1365-2958.2010.07351.x"
},
"PUB00064743": {
"PMID": 23273979,
"ISBN": null,
"volume": "49",
"issue": "3",
"year": 2013,
"title": "Conserved Bacterial RNase YbeY Plays Key Roles in 70S Ribosome Quality Control and 16S rRNA Maturation.",
"URL": null,
"raw_pages": "427-38",
"medline_journal": "Mol Cell",
"ISO_journal": "Mol. Cell",
"authors": [
"Jacob AI",
"Kohrer C",
"Davies BW",
"Rajbhandary UL",
"Walker GC."
],
"DOI_URL": "http://dx.doi.org/10.1016/j.molcel.2012.11.025"
},
"PUB00038326": {
"PMID": 16511207,
"ISBN": null,
"volume": "61",
"issue": "Pt 11",
"year": 2005,
"title": "The ybeY protein from Escherichia coli is a metalloprotein.",
"URL": null,
"raw_pages": "959-63",
"medline_journal": "Acta Crystallogr Sect F Struct Biol Cryst Commun",
"ISO_journal": "Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun.",
"authors": [
"Zhan C",
"Fedorov EV",
"Shi W",
"Ramagopal UA",
"Thirumuruhan R",
"Manjasetty BA",
"Almo SC",
"Fiser A",
"Chance MR",
"Fedorov AA."
],
"DOI_URL": "http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=EBI&pubmedid=16511207"
}
},
"set_info": null,
"overlaps_with": null,
"counters": {
"subfamilies": 0,
"domain_architectures": 0,
"interactions": 0,
"matches": 23364,
"pathways": 0,
"proteins": 23362,
"proteomes": 15634,
"sets": 0,
"structural_models": {
"alphafold": 18184,
"bfvd": 0
},
"structures": 5,
"taxa": 27873
},
"entry_annotations": {},
"cross_references": {},
"is_llm": false,
"is_reviewed_llm": false,
"is_updated_llm": false,
"representative_structure": null
}
}
