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{
    "metadata": {
        "accession": "IPR017124",
        "entry_id": null,
        "type": "family",
        "go_terms": [
            {
                "identifier": "GO:1990226",
                "name": "histone methyltransferase binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006366",
                "name": "transcription by RNA polymerase II",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "source_database": "interpro",
        "member_databases": {
            "pirsf": {
                "PIRSF037161": "PR-domain zinc finger protein PRDM4"
            }
        },
        "integrated": null,
        "hierarchy": {
            "accession": "IPR017124",
            "name": "PR-domain zinc finger protein PRDM4",
            "type": "Family",
            "children": []
        },
        "name": {
            "name": "PR-domain zinc finger protein PRDM4",
            "short": "PRDM4"
        },
        "description": [
            {
                "text": "<p>PRDM4 may function as a transcription factor that recruits protein arginine methyltransferase 5 (PRMT5) to mediate histone arginine methylation and control neural stem cell proliferation and differentiation  [[cite:PUB00078793]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00078793": {
                "PMID": 23048031,
                "ISBN": null,
                "volume": "287",
                "issue": "51",
                "year": 2012,
                "title": "Transcription factor positive regulatory domain 4 (PRDM4) recruits protein arginine methyltransferase 5 (PRMT5) to mediate histone arginine methylation and control neural stem cell proliferation and differentiation.",
                "URL": null,
                "raw_pages": "42995-3006",
                "medline_journal": "J Biol Chem",
                "ISO_journal": "J. Biol. Chem.",
                "authors": [
                    "Chittka A",
                    "Nitarska J",
                    "Grazini U",
                    "Richardson WD."
                ],
                "DOI_URL": "http://dx.doi.org/10.1074/jbc.M112.392746"
            }
        },
        "set_info": null,
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 0,
            "interactions": 0,
            "matches": 434,
            "pathways": 146,
            "proteins": 434,
            "proteomes": 268,
            "sets": 0,
            "structural_models": {
                "alphafold": 392,
                "bfvd": 0
            },
            "structures": 0,
            "taxa": 929
        },
        "entry_annotations": {},
        "cross_references": {
            "ec": {
                "displayName": "ENZYME",
                "description": "ENZYME is a repository of information relative to the nomenclature of enzymes. It is primarily based on the recommendations of the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (IUBMB) and it describes each type of characterized enzyme for which an EC (Enzyme Commission) number has been provided.",
                "rank": 19,
                "accessions": [
                    {
                        "accession": "2.1.1.-",
                        "url": "https://enzyme.expasy.org/EC/2.1.1.-"
                    }
                ]
            }
        },
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}