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{
    "metadata": {
        "accession": "IPR016214",
        "entry_id": null,
        "type": "family",
        "go_terms": null,
        "source_database": "interpro",
        "member_databases": {
            "pirsf": {
                "PIRSF000309": "NAD-reducing hydrogenase HoxS, gamma subunit"
            }
        },
        "integrated": null,
        "hierarchy": {
            "accession": "IPR016214",
            "name": "NAD-reducing hydrogenase, HoxS gamma subunit",
            "type": "Family",
            "children": []
        },
        "name": {
            "name": "NAD-reducing hydrogenase, HoxS gamma subunit",
            "short": "NAD-red_Hydgase_HoxS_gsu"
        },
        "description": [
            {
                "text": "<p>This entry represents the NAD-reducing hydrogenase HoxS gamma subunit (also known as HoxU). \r\nSubunits alpha and gamma of HoxS constitute a diaphorase sub-complex that binds a [2Fe2S] cluster, FMN and a series of [4Fe4S] clusters [[cite:PUB00060766], [cite:PUB00060767], [[cite:PUB00060933]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00060766": {
                "PMID": 9541559,
                "ISBN": null,
                "volume": "36",
                "issue": "5",
                "year": 1998,
                "title": "Unusual gene arrangement of the bidirectional hydrogenase and functional analysis of its diaphorase subunit HoxU in respiration of the unicellular cyanobacterium anacystis nidulans ",
                "URL": null,
                "raw_pages": "253-8",
                "medline_journal": "Curr Microbiol",
                "ISO_journal": "Curr. Microbiol.",
                "authors": [
                    "Boison G",
                    "Schmitz O",
                    "Schmitz B",
                    "Bothe H."
                ],
                "DOI_URL": "http://dx.doi.org/10.1007/s002849900305"
            },
            "PUB00060767": {
                "PMID": 12034472,
                "ISBN": null,
                "volume": "1554",
                "issue": "1-2",
                "year": 2002,
                "title": "HoxE--a subunit specific for the pentameric bidirectional hydrogenase complex (HoxEFUYH) of cyanobacteria.",
                "URL": null,
                "raw_pages": "66-74",
                "medline_journal": "Biochim Biophys Acta",
                "ISO_journal": "Biochim. Biophys. Acta",
                "authors": [
                    "Schmitz O",
                    "Boison G",
                    "Salzmann H",
                    "Bothe H",
                    "Schutz K",
                    "Wang SH",
                    "Happe T."
                ],
                "DOI_URL": "http://dx.doi.org/10.1016/S0005-2728(02)00214-1"
            },
            "PUB00060933": {
                "PMID": 22016788,
                "ISBN": null,
                "volume": "6",
                "issue": "10",
                "year": 2011,
                "title": "Catalytic properties of the isolated diaphorase fragment of the NAD-reducing [NiFe]-hydrogenase from Ralstonia eutropha.",
                "URL": null,
                "raw_pages": "e25939",
                "medline_journal": "PLoS One",
                "ISO_journal": "PLoS ONE",
                "authors": [
                    "Lauterbach L",
                    "Idris Z",
                    "Vincent KA",
                    "Lenz O."
                ],
                "DOI_URL": "http://dx.doi.org/10.1371/journal.pone.0025939"
            }
        },
        "set_info": null,
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 0,
            "interactions": 0,
            "matches": 789,
            "pathways": 0,
            "proteins": 789,
            "proteomes": 478,
            "sets": 0,
            "structural_models": {
                "alphafold": 655,
                "bfvd": 0
            },
            "structures": 2,
            "taxa": 1597
        },
        "entry_annotations": {},
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}