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{
    "metadata": {
        "accession": "IPR008622",
        "entry_id": null,
        "type": "family",
        "go_terms": null,
        "source_database": "interpro",
        "member_databases": {
            "hamap": {
                "MF_01180": "Flagellar protein FliT [fliT]"
            },
            "pfam": {
                "PF05400": "Flagellar protein FliT"
            }
        },
        "integrated": null,
        "hierarchy": {
            "accession": "IPR008622",
            "name": "Flagellar protein FliT",
            "type": "Family",
            "children": []
        },
        "name": {
            "name": "Flagellar protein FliT",
            "short": "FliT"
        },
        "description": [
            {
                "text": "<p>This entry represents the bacterial flagellar FliT family of dual-function proteins. Together with FlgN, FliT has been proposed to act as a substrate-specific export chaperone, facilitating the incorporation of the enterobacterial hook-associated axial proteins (HAPs) FlgK/FlgL and FliD into the growing flagellum [[cite:PUB00010163]]. FliT has also been shown to act as a transcriptional regulator in Salmonella typhimurium [[cite:PUB00054965]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00010163": {
                "PMID": 11169117,
                "ISBN": null,
                "volume": "39",
                "issue": "3",
                "year": 2001,
                "title": "Substrate complexes and domain organization of the Salmonella flagellar export chaperones FlgN and FliT.",
                "URL": null,
                "raw_pages": "781-91",
                "medline_journal": "Mol Microbiol",
                "ISO_journal": "Mol. Microbiol.",
                "authors": [
                    "Bennett JC",
                    "Thomas J",
                    "Fraser GM",
                    "Hughes C."
                ],
                "DOI_URL": "http://dx.doi.org/10.1046/j.1365-2958.2001.02268.x"
            },
            "PUB00054965": {
                "PMID": 10791024,
                "ISBN": null,
                "volume": "74",
                "issue": "6",
                "year": 1999,
                "title": "Two novel regulatory genes, fliT and fliZ, in the flagellar regulon of Salmonella.",
                "URL": null,
                "raw_pages": "287-92",
                "medline_journal": "Genes Genet Syst",
                "ISO_journal": "Genes Genet. Syst.",
                "authors": [
                    "Kutsukake K",
                    "Ikebe T",
                    "Yamamoto S."
                ],
                "DOI_URL": "http://dx.doi.org/10.1266/ggs.74.287"
            }
        },
        "set_info": null,
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 3,
            "interactions": 0,
            "matches": 5637,
            "pathways": 0,
            "proteins": 5637,
            "proteomes": 3263,
            "sets": 0,
            "structural_models": {
                "alphafold": 4272,
                "bfvd": 0
            },
            "structures": 9,
            "taxa": 5372
        },
        "entry_annotations": {
            "alignment:seed": 75,
            "alignment:full": 1538
        },
        "cross_references": {
            "gp": {
                "displayName": "Genome Properties",
                "description": "Genome properties is an annotation system whereby functional attributes can be assigned to a genome, based on the presence of a defined set of protein signatures within that genome.",
                "rank": 45,
                "accessions": [
                    {
                        "accession": "GenProp0881",
                        "url": "https://www.ebi.ac.uk/interpro/genomeproperties/genome-property/GenProp0881"
                    }
                ]
            }
        },
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}