General Handler

HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept

{
    "metadata": {
        "accession": "IPR007407",
        "entry_id": null,
        "type": "family",
        "go_terms": null,
        "source_database": "interpro",
        "member_databases": {
            "cdd": {
                "cd01829": "SGNH_hydrolase_peri2"
            },
            "pfam": {
                "PF04311": "Protein of unknown function (DUF459)"
            }
        },
        "integrated": null,
        "hierarchy": {
            "accession": "IPR007407",
            "name": "Protein of unknown function DUF459",
            "type": "Family",
            "children": []
        },
        "name": {
            "name": "Protein of unknown function DUF459",
            "short": "DUF459"
        },
        "description": [
            {
                "text": "<p>This is a putative periplasmic protein and a member of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases [[cite:PUB00005440]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00005440": {
                "PMID": 7610479,
                "ISBN": null,
                "volume": "20",
                "issue": "5",
                "year": 1995,
                "title": "A new family of lipolytic enzymes?",
                "URL": null,
                "raw_pages": "178-9",
                "medline_journal": "Trends Biochem Sci",
                "ISO_journal": "Trends Biochem. Sci.",
                "authors": [
                    "Upton C",
                    "Buckley JT."
                ],
                "DOI_URL": "http://dx.doi.org/10.1016/S0968-0004(00)89002-7"
            }
        },
        "set_info": null,
        "overlaps_with": [
            {
                "accession": "IPR036514",
                "name": "SGNH hydrolase superfamily",
                "type": "homologous_superfamily"
            }
        ],
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 13,
            "interactions": 0,
            "matches": 2285,
            "pathways": 0,
            "proteins": 2250,
            "proteomes": 1359,
            "sets": 0,
            "structural_models": {
                "alphafold": 1737,
                "bfvd": 0
            },
            "structures": 5,
            "taxa": 2333
        },
        "entry_annotations": {
            "alignment:seed": 126,
            "alignment:full": 773
        },
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": {
            "accession": "7trr",
            "name": "Structure of Neisseria gonorrhoeae peptidoglycan O-acetyltransferase B (PatB) with methylsulfonyl adduct"
        }
    }
}