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{
    "metadata": {
        "accession": "IPR003763",
        "entry_id": null,
        "type": "family",
        "go_terms": [
            {
                "identifier": "GO:0008715",
                "name": "CDP-diacylglycerol diphosphatase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0008654",
                "name": "phospholipid biosynthetic process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0016020",
                "name": "membrane",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            }
        ],
        "source_database": "interpro",
        "member_databases": {
            "ncbifam": {
                "NF003986": "CDP-diacylglycerol diphosphatase"
            },
            "hamap": {
                "MF_00319": "CDP-diacylglycerol pyrophosphatase [cdh]"
            },
            "pirsf": {
                "PIRSF001273": "CDP-diacylglycerol pyrophosphatase"
            },
            "pfam": {
                "PF02611": "CDP-diacylglycerol pyrophosphatase"
            }
        },
        "integrated": null,
        "hierarchy": {
            "accession": "IPR003763",
            "name": "CDP-diacylglycerol pyrophosphatase",
            "type": "Family",
            "children": [
                {
                    "accession": "IPR015993",
                    "name": "CDP-diacylglycerol pyrophosphatase, proteobacterial",
                    "type": "Family",
                    "children": []
                }
            ]
        },
        "name": {
            "name": "CDP-diacylglycerol pyrophosphatase",
            "short": "CDP-diacylglyc_Pase"
        },
        "description": [
            {
                "text": "<p>The CDP-diacylglycerol pyrophosphatases [ec:3.6.1.26] play a role in the regulation of phospholipid metabolism by inositol, as well as regulating the cellular levels of phosphatidylinositol [[cite:PUB00008242]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00008242": {
                "PMID": 11016943,
                "ISBN": null,
                "volume": "275",
                "issue": "52",
                "year": 2000,
                "title": "Regulation of the DPP1-encoded diacylglycerol pyrophosphate (DGPP) phosphatase by inositol and growth phase. Inhibition of DGPP phosphatase activity by CDP-diacylglyceron and activation of phosphatidylserine synthase activity by DGPP.",
                "URL": null,
                "raw_pages": "40887-96",
                "medline_journal": "J Biol Chem",
                "ISO_journal": "J. Biol. Chem.",
                "authors": [
                    "Oshiro J",
                    "Rangaswamy S",
                    "Chen X",
                    "Han GS",
                    "Quinn JE",
                    "Carman GM."
                ],
                "DOI_URL": "http://dx.doi.org/10.1074/jbc.M008144200"
            }
        },
        "set_info": null,
        "overlaps_with": [
            {
                "accession": "IPR036265",
                "name": "HIT-like superfamily",
                "type": "homologous_superfamily"
            }
        ],
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 5,
            "interactions": 0,
            "matches": 2609,
            "pathways": 0,
            "proteins": 2608,
            "proteomes": 975,
            "sets": 0,
            "structural_models": {
                "alphafold": 2180,
                "bfvd": 0
            },
            "structures": 1,
            "taxa": 2032
        },
        "entry_annotations": {
            "alignment:seed": 28,
            "alignment:full": 384
        },
        "cross_references": {
            "ec": {
                "displayName": "ENZYME",
                "description": "ENZYME is a repository of information relative to the nomenclature of enzymes. It is primarily based on the recommendations of the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (IUBMB) and it describes each type of characterized enzyme for which an EC (Enzyme Commission) number has been provided.",
                "rank": 19,
                "accessions": [
                    {
                        "accession": "3.6.1.26",
                        "url": "https://enzyme.expasy.org/EC/3.6.1.26"
                    }
                ]
            }
        },
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": {
            "accession": "2pof",
            "name": "Crystal structure of CDP-diacylglycerol pyrophosphatase"
        }
    }
}