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{
    "metadata": {
        "accession": "IPR003379",
        "entry_id": null,
        "type": "domain",
        "go_terms": null,
        "source_database": "interpro",
        "member_databases": {
            "pfam": {
                "PF02436": "Conserved carboxylase domain"
            }
        },
        "integrated": null,
        "hierarchy": {
            "accession": "IPR003379",
            "name": "Carboxylase, conserved domain",
            "type": "Domain",
            "children": []
        },
        "name": {
            "name": "Carboxylase, conserved domain",
            "short": "Carboxylase_cons_dom"
        },
        "description": [
            {
                "text": "<p>This domain represents a conserved region in pyruvate carboxylase (PYC) ([ec:6.4.1.1]), oxaloacetate decarboxylase alpha chain (OADA) ([ec:4.1.1.3]), and transcarboxylase 5s subunit ([ec:2.1.3.1]). The domain is found adjacent to the HMGL-like domain ([interpro:IPR000891]) and often close to the biotin_lipoyl domain ([interpro:IPR000089]) of biotin requiring enzymes.</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": null,
        "set_info": null,
        "overlaps_with": [
            {
                "accession": "IPR013785",
                "name": "Aldolase-type TIM barrel",
                "type": "homologous_superfamily"
            }
        ],
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 117,
            "interactions": 0,
            "matches": 24885,
            "pathways": 25,
            "proteins": 24841,
            "proteomes": 11853,
            "sets": 0,
            "structural_models": {
                "alphafold": 20667,
                "bfvd": 0
            },
            "structures": 55,
            "taxa": 22713
        },
        "entry_annotations": {
            "alignment:seed": 318,
            "alignment:full": 8869
        },
        "cross_references": {
            "ec": {
                "displayName": "ENZYME",
                "description": "ENZYME is a repository of information relative to the nomenclature of enzymes. It is primarily based on the recommendations of the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (IUBMB) and it describes each type of characterized enzyme for which an EC (Enzyme Commission) number has been provided.",
                "rank": 19,
                "accessions": [
                    {
                        "accession": "6.4.1.1",
                        "url": "https://enzyme.expasy.org/EC/6.4.1.1"
                    }
                ]
            }
        },
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}