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InterPro-Version: 108.0
InterPro-Version-Minor: 0
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{
"metadata": {
"accession": "IPR001207",
"entry_id": null,
"type": "family",
"go_terms": [
{
"identifier": "GO:0003677",
"name": "DNA binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0004803",
"name": "transposase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0006313",
"name": "DNA transposition",
"category": {
"code": "P",
"name": "biological_process"
}
}
],
"source_database": "interpro",
"member_databases": {
"prosite": {
"PS01007": "Transposases, Mutator family, signature"
},
"pfam": {
"PF00872": "Transposase, Mutator family"
},
"panther": {
"PTHR33217": "TRANSPOSASE FOR INSERTION SEQUENCE ELEMENT IS1081"
}
},
"integrated": null,
"hierarchy": {
"accession": "IPR001207",
"name": "Transposase, mutator type",
"type": "Family",
"children": [
{
"accession": "IPR048004",
"name": "Transposase IS1249",
"type": "Family",
"children": []
}
]
},
"name": {
"name": "Transposase, mutator type",
"short": "Transposase_mutator"
},
"description": [
{
"text": "<p>Autonomous mobile genetic elements such as transposon or insertion sequences (IS) encode an enzyme, transposase, that is required for excising and inserting the mobile element. Transposases have been grouped into various families [[cite:PUB00004452], [cite:PUB00003820], [cite:PUB00001812]]. The mutator family of transposases consists of a number of elements that include, mutator from maize, IsT2 from Thiobacillus ferrooxidans, Is256 from Staphylococcus aureus, Is1201 from Lactobacillus helveticus, Is1081 from Mycobacterium bovis, IsRm3 from Rhizobium meliloti and others.</p>",
"llm": false,
"checked": false,
"updated": false
}
],
"wikipedia": null,
"literature": {
"PUB00001812": {
"PMID": 1718819,
"ISBN": null,
"volume": "105",
"issue": "1",
"year": 1991,
"title": "IS406 and IS407, two gene-activating insertion sequences for Pseudomonas cepacia.",
"URL": null,
"raw_pages": "101-5",
"medline_journal": "Gene",
"ISO_journal": "Gene",
"authors": [
"Wood MS",
"Byrne A",
"Lessie TG."
],
"DOI_URL": "http://dx.doi.org/10.1016/0378-1119(91)90519-H"
},
"PUB00004452": {
"PMID": 8041625,
"ISBN": null,
"volume": "22",
"issue": "13",
"year": 1994,
"title": "Sequence similarity of putative transposases links the maize Mutator autonomous element and a group of bacterial insertion sequences.",
"URL": null,
"raw_pages": "2634-6",
"medline_journal": "Nucleic Acids Res",
"ISO_journal": "Nucleic Acids Res.",
"authors": [
"Eisen JA",
"Benito MI",
"Walbot V."
],
"DOI_URL": "http://dx.doi.org/10.1093/nar/22.13.2634"
},
"PUB00003820": {
"PMID": 1310791,
"ISBN": null,
"volume": "6",
"issue": "1",
"year": 1992,
"title": "Isolation and analysis of IS6120, a new insertion sequence from Mycobacterium smegmatis.",
"URL": null,
"raw_pages": "107-13",
"medline_journal": "Mol Microbiol",
"ISO_journal": "Mol. Microbiol.",
"authors": [
"Guilhot C",
"Gicquel B",
"Davies J",
"Martin C."
],
"DOI_URL": "http://dx.doi.org/10.1111/j.1365-2958.1992.tb00842.x"
}
},
"set_info": null,
"overlaps_with": null,
"counters": {
"subfamilies": 0,
"domain_architectures": 139,
"interactions": 0,
"matches": 31127,
"pathways": 0,
"proteins": 30981,
"proteomes": 6179,
"sets": 0,
"structural_models": {
"alphafold": 24480,
"bfvd": 0
},
"structures": 3,
"taxa": 12984
},
"entry_annotations": {
"alignment:seed": 7,
"alignment:full": 10433
},
"cross_references": {
"prositedoc": {
"displayName": "PROSITE Doc",
"description": "PROSITE is a database of protein families and domains.",
"rank": 18,
"accessions": [
{
"accession": "PDOC00770",
"url": "http://prosite.expasy.org/PDOC00770"
}
]
}
},
"is_llm": false,
"is_reviewed_llm": false,
"is_updated_llm": false,
"representative_structure": null
}
}