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{
    "metadata": {
        "accession": "IPR000938",
        "entry_id": null,
        "type": "domain",
        "go_terms": null,
        "source_database": "interpro",
        "member_databases": {
            "smart": {
                "SM01052": "CAP_GLY"
            },
            "profile": {
                "PS50245": "CAP-Gly domain profile"
            },
            "prosite": {
                "PS00845": "CAP-Gly domain signature"
            },
            "pfam": {
                "PF01302": "CAP-Gly domain"
            }
        },
        "integrated": null,
        "hierarchy": {
            "accession": "IPR000938",
            "name": "CAP Gly-rich domain",
            "type": "Domain",
            "children": []
        },
        "name": {
            "name": "CAP Gly-rich domain",
            "short": "CAP-Gly_domain"
        },
        "description": [
            {
                "text": "<p>Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved glycine-rich domain, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of the Caenorhabditis elegans F53F4.3 protein CAP-Gly domain has been solved. The domain contains three β-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove [[cite:PUB00015605]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00015605": {
                "PMID": 12221106,
                "ISBN": null,
                "volume": "277",
                "issue": "50",
                "year": 2002,
                "title": "Crystal structure of the cytoskeleton-associated protein glycine-rich (CAP-Gly) domain.",
                "URL": null,
                "raw_pages": "48596-601",
                "medline_journal": "J Biol Chem",
                "ISO_journal": "J. Biol. Chem.",
                "authors": [
                    "Li S",
                    "Finley J",
                    "Liu ZJ",
                    "Qiu SH",
                    "Chen H",
                    "Luan CH",
                    "Carson M",
                    "Tsao J",
                    "Johnson D",
                    "Lin G",
                    "Zhao J",
                    "Thomas W",
                    "Nagy LA",
                    "Sha B",
                    "DeLucas LJ",
                    "Wang BC",
                    "Luo M."
                ],
                "DOI_URL": "http://dx.doi.org/10.1074/jbc.M208512200"
            }
        },
        "set_info": null,
        "overlaps_with": [
            {
                "accession": "IPR036859",
                "name": "CAP Gly-rich domain superfamily",
                "type": "homologous_superfamily"
            }
        ],
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 750,
            "interactions": 0,
            "matches": 48022,
            "pathways": 102,
            "proteins": 35836,
            "proteomes": 3379,
            "sets": 0,
            "structural_models": {
                "alphafold": 23149,
                "bfvd": 0
            },
            "structures": 54,
            "taxa": 9665
        },
        "entry_annotations": {
            "alignment:seed": 532,
            "alignment:full": 31323
        },
        "cross_references": {
            "prositedoc": {
                "displayName": "PROSITE Doc",
                "description": "PROSITE is a database of protein families and domains.",
                "rank": 18,
                "accessions": [
                    {
                        "accession": "PDOC00660",
                        "url": "http://prosite.expasy.org/PDOC00660"
                    }
                ]
            }
        },
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": {
            "accession": "3rdv",
            "name": "Structure of the SLAIN2c-CLIPCG1 complex"
        }
    }
}