GPBAR1 agonism has a broad impact on blocking macrophage activation
RNA-Seq mRNA differential
Organism:
Homo sapiens
Publication
- Lewis ND, Patnaude LA, Pelletier J, Souza DJ, Lukas SM et al. (2014) A GPBAR1 (TGR5) small molecule agonist shows specific inhibitory effects on myeloid cell activation in vitro and reduces experimental autoimmune encephalitis (EAE) in vivo.