27th Annual Workshop on Mathematical and Statistical Aspects of Molecular Biology

April 3-4, 2017 @ Vienna, Austria

Bioinformatics and statistical genetics, twin themes of the long-running series of annual MASAMB meetings, have gained huge impetus from large-scale genome sequencing projects and development of high-throughput biological assay systems, including gene-expression microarrays, proteomic, metabolomic and single-cell genomics technologies. These immense data resources, and the underlying complexities of molecular and cell biology, provide exciting research opportunities for numerate scientists.

With typically around 80-120 participants from mathematics, statistics, computer science, bioinformatics, biology and related fields, the MASAMB meetings provide an intimate setting for exchanging ideas in methodological and applied research. Research students and scientists newly entering the field of genomic research are particularly welcome and encouraged to submit abstracts. Details of previous meetings are available at the MASAMB archive.

Likely topics for sessions this year

Next Generation Sequencing
Population Genetics
RNA Bioinformatics
Phylogeny and Comparative Genomics
Personalised medicine
Biological Networks
Systems Biology
Registration opens December 15th, 2016
Abstract submission deadline February 15th, March 3rd, 2017
Registration ends March 10th, 2017
Conference April 3rd-4th, 2017

Monday, April 3rd

11:00-13.45 Registration
12:45-13.45 Lunch
13:45-14:00 Welcome and Introduction

SESSION 1: Systems Biology and Biological Networks

14:00-14:20 Thalia Chan, Ann Babtie and Michael Stumpf
"Network inference using multivariate information measures"
14:20-14:40 Ivan Croydon Veleslavov, Duncan Ingram, Daria Dicu, Furan Wang and Michael Stumpf
"Presenting Waddle: A Waddington Landscape Engine"
14:40-15:00 Klaudia Walter, Alice L. Mann, Kate Waller, Anton Tool, Willem H. Ouwehand, T.W. Kuijpers, Kate Downes and Nicole Soranzo
"Genetic variation in the first line of immune defense: exploring genome-wide associations in of human neutrophils"
15:00-15:20 Magdalena Strauss, Lorenz Wernisch and John Reid
"New MCMC methods for pseudo-time estimation using Gaussian processes"
15:20-15:40 Jing Yang and Magnus Rattray
"Gaussian process inference of time-varying mRNA degradation"
15:40-16:00 Holger Bergmann, Vinh Tran, Ingo Ebersberger and Julian Dosch
"Tracing functional protein interaction networks using a ‘feature-aware’ phylogenetic profiling"


SESSION 2: Medical applications

16:30-16:50 Benedikt Rauscher, Florian Heigwer, Luisa Henkel, Thomas Hielscher and Michael Boutros
"A Map of Genetic Interactions in Cancer Cells"
16:50-17:10 Florian Halbritter, Matthias Farlik, Fabian Müller and Christoph Bock
"Charting and understanding normal and abnormal cellular differentiation hierarchies"
17:10-17:30 Svetlana Ovchinnikova and Simon Anders
"The Linked-charts JavaScript Library to Assist Omics Data Exploration"


20:00 Conference Dinner

Tuesday, April 4th

SESSION 3: Population Genetics

09:00-09:20 Agnes Jonas, Thomas Taus, Carolin Kosiol, Christian Schlötterer and Andreas Futschik
"Estimating the Effective Population Size from Temporal Allele Frequency Changes in Experimental Evolution"
09:20-09:40 Claus Vogl, Juraj Bergman and Dominik Schrempf
"Inference in population genetics from site frequency spectra using forward and backward diffusion"
09:40-10:00 Samuele Soraggi, Carsten Wiuf and Anders Albrechtsen
"Improved D-statistic for low-coverage data"
10:00-10:20 Carolin Kosiol, Nicola De Maio and Dominik Schrempf
"Polymorphism-Aware Phylogenetic Model (PoMo): Disentangling mutation, directional and balancing selection"
10:20-10:40 Nicola De Maio and Daniel Wilson
"The bacterial sequential Markov coalescent"

COFFEE BREAK + Vote for the next MASAMB meeting

SESSION 4: Next Generation Sequencing

11:20-11:40 Paweł P. Łabaj and David P. Kreil
"Reference sample for reliable differential expression calls across lab"
11:40-12:00 Celine Prakash, Florian Pflug and Arndt von Haeseler
"An Enumerative Combinatorics Approach to Analysing Fragmentation Patterns in RNA Sequencing"
12:00-12:20 Pooja Bhat, Veronika Herzog, Tobias Neumann, Philipp Philipp Rescheneder and Stefan Ameres
"Refining the annotation of mRNA 3’ ends using 3’ end sequencing data"
12:20-12:40 Tommi Mäklin, Jukka Corander and Antti Honkela
"Bayesian identification of bacterial strains and quantification of strain mixtures"
12:40-13:00 Na Cai, Nicole Soranzo and Oliver Stegle
"Tissue specific mitochondrial control of gene expression"


SESSION 5: Comparative genomics and Evolution

14:20-14:40 Gergely J Szöllősi, Adrián A Davín, Eric Tannier, Bastien Boussau and Vincent Daubin
"Gene transfers, like fossils, can date the tree of life"
14:40-15:00 Dominik Schrempf and Carolin Kosiol
"Exome-wide phylogenetic analysis of Papio baboons with polymorphism-aware models"
15:00-15:20 Arpit Jain, Bui Quang Minh, Arndt Von Haeseler and Ingo Ebersberger
"The evolutionary dynamics of protein domains"
15:20-15:40 Marcin Bogusz and Simon Whelan
"Fast statistical method of obtaining dN/dS and indel rate estimates from unaligned protein coding sequences"
15:40-16:00 Eran Elhaik
"From lost empires to modern cities with ancient GPS"


To register, please, contact Iris Gruber (iris.gruber(at)

The registration fees are

  • 85 € for students
  • 120 € for researchers
  • 200 € for industry participants
Fees include conference attendance, coffee, drinks reception and conference dinner on the 3d of April.

A one-half page abstract should be submitted through EasyChair. Please choose two session titles from likely topics that most closely match the topic of your talk/poster and enter them as Keyword 1 and Keyword 2. Other keywords can be added as wished. Note that abstracts will only be considered after an online registration form has been filled and the registration fees have been paid.

Andreas Futschik, JKU, Austria
Arndt von Haeseler, CIBIV, Austria
Bui Quang Minh, CIBIV, Austria
Carolin Kosiol, Vetmeduni Vienna, Austria
David P. Kreil, BOKU, Austria
Fabio Pardi, LIRMM, France
Ingo Ebersberger, Goethe-Universität, Germany
Jonathan Bollback, IST Austria
Thomas Rattei, CUBE, University of Vienna, Austria

Arndt von Haeseler, CIBIV, Austria
Olga Chernomor, CIBIV, Austria
Iris Gruber, CIBIV, Austria
The registration and conference will take place in the Institute of Molecular Biotechnology (IMBA main lecture hall, 1st floor).

Here is the full address of the venue:
IMBA - Institute of Molecular Biotechnology GmbH
Dr. Bohr Gasse 3, 1030 Vienna, Austria

For additional information visit

The following hotels have reserved rooms for participants of the workshop. Please contact respective hotel directly to book accomodation, with reference to the MASAMB conference.


Rennweg 51, A-1030 Wien
Tel.: 0043 1 7132521-248
Fax: 0043 1 890 15 91
Rooms: 30 single rooms (EUR 69/person) + 2 double rooms (EUR 44,50/Person)

Hotel Pribitzer
Rooms: single rooms (EUR 50/person) + 4 double rooms (EUR 60/Person)

Resonanz Hotel
contact Velibor Marinkovic
Rooms: 3 single rooms (EUR 70/person) + 2-3 double rooms (EUR 90/room)

Hotel Regina
Email contact Mrs. Thanhäuser:
Rooms: 15 single rooms (EUR 100/room) + 15 double rooms (EUR 150/room) incl breakfast and WLan. Fill out the form and send it with your reservation.