Foci/cell: the average numbers of 53BP1 foci per cell on each siRNA spot
f_c
Foci number
fn
Cell number
n
Norm foci/cell: the Foci/cell values normalized by the average number of 53BP1 foci/cell on spots with non-targeting control siRNAs present on the same plate
n_fn
Z score: Z = (X - μ) / σ, where X is Norm foci/cell, μ is the mean of Norm foci/cell for all siRNAs and σ is the standard deviation of Norm foci/cell for all siRNAs
z
— phenotypes are defined directly in the study's spreadsheet