tetrahydrofolyl-poly(glutamic acid) macromolecule (CHEBI:28624)

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CHEBI:28624 - tetrahydrofolyl-poly(glutamic acid) macromolecule

ChEBI ID	CHEBI:28624
ChEBI Name	tetrahydrofolyl-poly(glutamic acid) macromolecule
Stars
Definition	A tetrahydrofolyl glutamate consisting of a tetrahydrofolyl group linked via an amide bond to a poly(γ-glutamyl chain)
Secondary ChEBI IDs	CHEBI:9484, CHEBI:26910
Last Modified	3 February 2017
Downloads	Molfile

Formula	(C5H7NO3)n.C19H23N7O6
Net Charge	0
Average Mass	574.551
Monoisotopic Mass	574.21357
SMILES	Nc1nc2c(c(=O)n1)NC(CNc1ccc(C(=O)NC(CCC(=O)NC(CCC(=O)O)C(=O)O)C(=O)O)cc1)CN2
InChI	InChI=1S/C24H30N8O9/c25-24-31-19-18(21(37)32-24)28-13(10-27-19)9-26-12-3-1-11(2-4-12)20(36)30-15(23(40)41)5-7-16(33)29-14(22(38)39)6-8-17(34)35/h1-4,13-15,26,28H,5-10H2,(H,29,33)(H,30,36)(H,34,35)(H,38,39)(H,40,41)(H4,25,27,31,32,37)
InChIKey	ZAOGJXDWOQXFBW-UHFFFAOYSA-N

Species of Metabolite	Component	Source	Comments
Mus musculus (ncbitaxon:10090)	-	PubMed (19425150)	Source: BioModels - MODEL1507180067

Roles Classification

Biological Roles:

mouse metabolite Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).

water-soluble vitamin (role) Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine.

Application:

nutraceutical A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance.

ChEBI Ontology

Outgoing Relation(s)
	tetrahydrofolyl-poly(glutamic acid) macromolecule (CHEBI:28624) has role mouse metabolite (CHEBI:75771)
	tetrahydrofolyl-poly(glutamic acid) macromolecule (CHEBI:28624) is a tetrahydrofolyl glutamate (CHEBI:26908)
	tetrahydrofolyl-poly(glutamic acid) macromolecule (CHEBI:28624) is conjugate acid of tetrahydrofolyl-poly(glutamate) macromolecule (CHEBI:58580)
Incoming Relation(s)
	tetrahydrofolyl-poly(glutamic acid) polymer (CHEBI:68515) has part tetrahydrofolyl-poly(glutamic acid) macromolecule (CHEBI:28624)
	tetrahydrofolyl-poly(L-glutamic acid) macromolecule (CHEBI:68512) is a tetrahydrofolyl-poly(glutamic acid) macromolecule (CHEBI:28624)
	tetrahydrofolyl-poly(glutamate) macromolecule (CHEBI:58580) is conjugate base of tetrahydrofolyl-poly(glutamic acid) macromolecule (CHEBI:28624)

IUPAC Name
N-[(4-{[(2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)carbonyl]poly(γ-glutamyl)glutamic acid

Synonyms	Source
tetrahydrofolyl-(Glu)_n	ChEBI
Tetrahydrofolyl-[Glu](n)	KEGG COMPOUND
Tetrahydrofolyl-[Glu](n+1)	KEGG COMPOUND
Tetrahydropteroyl-[gamma-Glu]n	KEGG COMPOUND
Tetrahydropteroyl-[gamma-Glu]n+1	KEGG COMPOUND
THF-polyglutamate	KEGG COMPOUND

Manual Xrefs	Databases
C03541	KEGG COMPOUND