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CHEBI:138502 - etazolate
| Formula | C14H19N5O2 |
| Net Charge | 0 |
| Average Mass | 289.339 |
| Monoisotopic Mass | 289.15387 |
| SMILES | CCOC(=O)c1cnc2c(cnn2CC)c1NN=C(C)C |
| InChI | InChI=1S/C14H19N5O2/c1-5-19-13-10(8-16-19)12(18-17-9(3)4)11(7-15-13)14(20)21-6-2/h7-8H,5-6H2,1-4H3,(H,15,18) |
| InChIKey | OPQRBXUBWHDHPQ-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | alpha-secretase activator An activator of α-secretase, one of the three endopeptidases that are specific for amyloid protein precursor and which have been identified based upon the region of the amyloid protein precursor which they cleave. phosphodiesterase IV inhibitor An EC 3.1.4.53 (3',5'-cyclic-AMP phosphodiesterase) inhibitor that specifically blocks the action of phosphodiesterase IV. GABA agent A substance, such as agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function, used for its pharmacological actions on GABAergic systems. |
| Applications: | antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. GABA agent A substance, such as agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function, used for its pharmacological actions on GABAergic systems. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| etazolate (CHEBI:138502) has role antidepressant (CHEBI:35469) |
| etazolate (CHEBI:138502) has role antipsychotic agent (CHEBI:35476) |
| etazolate (CHEBI:138502) has role anxiolytic drug (CHEBI:35474) |
| etazolate (CHEBI:138502) has role GABA agent (CHEBI:51374) |
| etazolate (CHEBI:138502) has role neuroprotective agent (CHEBI:63726) |
| etazolate (CHEBI:138502) has role phosphodiesterase IV inhibitor (CHEBI:68844) |
| etazolate (CHEBI:138502) has role α-secretase activator (CHEBI:88355) |
| etazolate (CHEBI:138502) is a ethyl ester (CHEBI:23990) |
| etazolate (CHEBI:138502) is a hydrazone (CHEBI:38532) |
| etazolate (CHEBI:138502) is a pyrazolopyridine (CHEBI:46699) |
| IUPAC Name |
|---|
| ethyl 1-ethyl-4-(2-isopropylidenehydrazino)-1H-pyrazolo[3,4-b]pyridine-5-carboxylate |
| INNs | Source |
|---|---|
| etazolato | WHO MedNet |
| étazolate | WHO MedNet |
| etazolatum | WHO MedNet |
| etazolate | WHO MedNet |
| Synonyms | Source |
|---|---|
| 1H-pyrazolo(3,4-b)pyridine-5-carboxylic acid, 1-ethyl-4-((1-methylethylidene)hydrazino)-, ethyl ester | SUBMITTER |
| ethyl 1-ethyl-4-(2-isopropylidenehydrazino)pyrazolo[3,4-b]pyridine-5-carboxylate | SUBMITTER |
| ethyl 1-ethyl-4-(2-propan-2-ylidenehydrazinyl)pyrazolo[3,4-b]pyridine-5-carboxylate | SUBMITTER |
| ethyl 1-ethyl-4-(2-propan-2-ylidenehydrazinyl)pyrazolo[4,5-e]pyridine-5-carboxylate | SUBMITTER |
| ethyl 1-ethyl-4-[2-(1-methylethylidene)hydrazino]-1H-pyrazolo[3,4-b]pyridine-5-carboxylate | SUBMITTER |
| 1-ethyl-4-(2-propan-2-ylidenehydrazinyl)-5-pyrazolo[3,4-b]pyridinecarboxylic acid ethyl ester | LINCS |
| Registry Numbers | Sources |
|---|---|
| Reaxys:548872 | Reaxys |
| CAS:51022-77-6 | ChemIDplus |
| Citations |
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