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CHEBI:37550 - sphingosine 1-phosphate

ChEBI IDCHEBI:37550
ChEBI Namesphingosine 1-phosphate
Stars
DefinitionA phosphosphingolipid that consists of sphingosine having a phospho group attached at position 1
Secondary ChEBI IDsCHEBI:9225, CHEBI:26742
Last Modified27 January 2016
DownloadsMolfile
FormulaC18H38NO5P
Net Charge0
Average Mass379.478
Monoisotopic Mass379.24876
SMILESCCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)COP(=O)(O)O
InChIInChI=1S/C18H38NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h14-15,17-18,20H,2-13,16,19H2,1H3,(H2,21,22,23)/b15-14+/t17-,18+/m0/s1
InChIKeyDUYSYHSSBDVJSM-KRWOKUGFSA-N
Wikipedia
Species of MetaboliteComponentSourceComments
Mus musculus (ncbitaxon:10090)
- MetaboLights (MTBLS143)
- PubMed (19425150) Source: BioModels - MODEL1507180067
Roles Classification
Biological Roles:
sphingosine-1-phosphate receptor agonist  An agonist that binds to and activates sphingosine 1-phosphate receptors.
mouse metabolite  Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
signalling molecule  A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell.
T-cell proliferation inhibitor  An inhibitor that interferes with the process of T-cell proliferation.
Application:
vasodilator agent  A drug used to cause dilation of the blood vessels.
ChEBI Ontology
Outgoing Relation(s)
sphingosine 1-phosphate (CHEBI:37550) has functional parent sphingosine (CHEBI:16393)
sphingosine 1-phosphate (CHEBI:37550) has role mouse metabolite (CHEBI:75771)
sphingosine 1-phosphate (CHEBI:37550) has role signalling molecule (CHEBI:62488)
sphingosine 1-phosphate (CHEBI:37550) has role sphingosine-1-phosphate receptor agonist (CHEBI:63114)
sphingosine 1-phosphate (CHEBI:37550) has role T-cell proliferation inhibitor (CHEBI:63173)
sphingosine 1-phosphate (CHEBI:37550) has role vasodilator agent (CHEBI:35620)
sphingosine 1-phosphate (CHEBI:37550) is a sphingoid 1-phosphate (CHEBI:77068)
sphingosine 1-phosphate (CHEBI:37550) is conjugate acid of sphingosine 1-phosphate(1−) (CHEBI:60119)
Incoming Relation(s)
sphingosine 1-phosphate(1−) (CHEBI:60119) is conjugate base of sphingosine 1-phosphate (CHEBI:37550)
IUPAC Name 
(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate
Synonyms  Source
Sphingosine 1-phosphateKEGG COMPOUND
Sphing-4-enine 1-phosphateKEGG COMPOUND
(2S,3R,4E)-2-amino-4-octadecene-1,3-diol 1-(dihydrogen phosphate)ChemIDplus
sphingosine-1-phosphateChemIDplus
D-erythro-sphingosine 1-phosphateHMDB
(2-amino-3-hydroxy-octadec-4-enoxy)phosphonic acidHMDB
Manual XrefsDatabases
C06124KEGG COMPOUND
LMSP01050001LIPID MAPS
HMDB0000277HMDB
Sphingosine-1-phosphateWikipedia
Registry NumbersSources
Reaxys:5877213Reaxys
CAS:26993-30-6ChemIDplus
CAS:26993-30-6KEGG COMPOUND
Citations