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CHEBI:8364 - prazosin
| Formula | C19H21N5O4 |
| Net Charge | 0 |
| Average Mass | 383.408 |
| Monoisotopic Mass | 383.15935 |
| SMILES | COc1cc2nc(N3CCN(C(=O)c4ccco4)CC3)nc(N)c2cc1OC |
| InChI | InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22) |
| InChIKey | IENZQIKPVFGBNW-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | alpha-adrenergic antagonist An agent that binds to but does not activate α-adrenergic receptors thereby blocking the actions of endogenous or exogenous α-adrenergic agonists. α-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma. EC 3.4.21.26 (prolyl oligopeptidase) inhibitor Any EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of prolyl oligopeptidase (EC 3.4.21.26). |
| Applications: | alpha-adrenergic antagonist An agent that binds to but does not activate α-adrenergic receptors thereby blocking the actions of endogenous or exogenous α-adrenergic agonists. α-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| prazosin (CHEBI:8364) has role antihypertensive agent (CHEBI:35674) |
| prazosin (CHEBI:8364) has role EC 3.4.21.26 (prolyl oligopeptidase) inhibitor (CHEBI:76779) |
| prazosin (CHEBI:8364) has role α-adrenergic antagonist (CHEBI:37890) |
| prazosin (CHEBI:8364) is a aromatic ether (CHEBI:35618) |
| prazosin (CHEBI:8364) is a furans (CHEBI:24129) |
| prazosin (CHEBI:8364) is a monocarboxylic acid amide (CHEBI:29347) |
| prazosin (CHEBI:8364) is a piperazines (CHEBI:26144) |
| prazosin (CHEBI:8364) is a quinazolines (CHEBI:38530) |
| Incoming Relation(s) |
| prazosin hydrochloride (CHEBI:8365) has part prazosin (CHEBI:8364) |
| IUPAC Name |
|---|
| 2-[4-(2-furoyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine |
| INNs | Source |
|---|---|
| prazosin | WHO MedNet |
| prazosinum | WHO MedNet |
| prazosine | WHO MedNet |
| prazosina | WHO MedNet |
| Synonyms | Source |
|---|---|
| 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine | ChemIDplus |
| 2-(4-(2-Furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline | ChemIDplus |
| Citations |
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