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CHEBI:8364 - prazosin
| Formula | C19H21N5O4 |
| Net Charge | 0 |
| Average Mass | 383.408 |
| Monoisotopic Mass | 383.15935 |
| SMILES | COc1cc2nc(N3CCN(C(=O)c4ccco4)CC3)nc(N)c2cc1OC |
| InChI | InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22) |
| InChIKey | IENZQIKPVFGBNW-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | antiviral agent A substance that destroys or inhibits replication of viruses. EC 3.4.21.26 (prolyl oligopeptidase) inhibitor Any EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of prolyl oligopeptidase (EC 3.4.21.26). alpha-adrenergic antagonist An agent that binds to but does not activate α-adrenergic receptors thereby blocking the actions of endogenous or exogenous α-adrenergic agonists. α-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma. |
| Applications: | anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. alpha-adrenergic antagonist An agent that binds to but does not activate α-adrenergic receptors thereby blocking the actions of endogenous or exogenous α-adrenergic agonists. α-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma. |
| ChEBI Ontology |
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| Outgoing Relation(s) |
| prazosin (CHEBI:8364) has role antidepressant (CHEBI:35469) |
| prazosin (CHEBI:8364) has role antihypertensive agent (CHEBI:35674) |
| prazosin (CHEBI:8364) has role antiviral agent (CHEBI:22587) |
| prazosin (CHEBI:8364) has role anxiolytic drug (CHEBI:35474) |
| prazosin (CHEBI:8364) has role EC 3.4.21.26 (prolyl oligopeptidase) inhibitor (CHEBI:76779) |
| prazosin (CHEBI:8364) has role α-adrenergic antagonist (CHEBI:37890) |
| prazosin (CHEBI:8364) is a aromatic ether (CHEBI:35618) |
| prazosin (CHEBI:8364) is a furans (CHEBI:24129) |
| prazosin (CHEBI:8364) is a monocarboxylic acid amide (CHEBI:29347) |
| prazosin (CHEBI:8364) is a piperazines (CHEBI:26144) |
| prazosin (CHEBI:8364) is a quinazolines (CHEBI:38530) |
| Incoming Relation(s) |
| prazosin hydrochloride (CHEBI:8365) has part prazosin (CHEBI:8364) |
| IUPAC Name |
|---|
| 2-[4-(2-furoyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine |
| INNs | Source |
|---|---|
| prazosin | WHO MedNet |
| prazosina | WHO MedNet |
| prazosine | WHO MedNet |
| prazosinum | WHO MedNet |
| Synonyms | Source |
|---|---|
| 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine | ChemIDplus |
| 2-(4-(2-Furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline | ChemIDplus |
| CP-122991 | ChEMBL |
| Citations |
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