EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:68845 - azilsartan medoxomil

Default Structure
ChEBI IDCHEBI:68845
ChEBI Nameazilsartan medoxomil
Stars
DefinitionA carboxylic ester obtained by formal condensation of the carboxy group of azilsartan with the hydroxy group of 4-(hydroxymethyl)-5-methyl-1,3-dioxol-2-one. A prodrug for azilsartan, it is used for treatment of hypertension.
Last Modified22 February 2017
SubmitterSteve
DownloadsMolfile
FormulaC30H24N4O8
Net Charge0
Average Mass568.542
Monoisotopic Mass568.15941
SMILESCCOc1nc2cccc(C(=O)OCc3oc(=O)oc3C)c2n1Cc1ccc(-c2ccccc2-c2noc(=O)n2)cc1
InChIInChI=1S/C30H24N4O8/c1-3-38-28-31-23-10-6-9-22(27(35)39-16-24-17(2)40-30(37)41-24)25(23)34(28)15-18-11-13-19(14-12-18)20-7-4-5-8-21(20)26-32-29(36)42-33-26/h4-14H,3,15-16H2,1-2H3,(H,32,33,36)
InChIKeyQJFSABGVXDWMIW-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Role:
angiotensin receptor antagonist  A hormone antagonist that blocks angiotensin receptors.
Applications:
prodrug  A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
antihypertensive agent  Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
angiotensin receptor antagonist  A hormone antagonist that blocks angiotensin receptors.
ChEBI Ontology
Outgoing Relation(s)
azilsartan medoxomil (CHEBI:68845) has functional parent azilsartan (CHEBI:68850)
azilsartan medoxomil (CHEBI:68845) has role angiotensin receptor antagonist (CHEBI:61016)
azilsartan medoxomil (CHEBI:68845) has role antihypertensive agent (CHEBI:35674)
azilsartan medoxomil (CHEBI:68845) has role prodrug (CHEBI:50266)
azilsartan medoxomil (CHEBI:68845) is a 1,2,4-oxadiazole (CHEBI:46809)
azilsartan medoxomil (CHEBI:68845) is a aromatic ether (CHEBI:35618)
azilsartan medoxomil (CHEBI:68845) is a benzimidazoles (CHEBI:22715)
azilsartan medoxomil (CHEBI:68845) is a carboxylic ester (CHEBI:33308)
azilsartan medoxomil (CHEBI:68845) is a cyclic carbonate ester (CHEBI:46838)
azilsartan medoxomil (CHEBI:68845) is a dioxolane (CHEBI:39430)
azilsartan medoxomil (CHEBI:68845) is conjugate acid of azilsartan medoxomil(1−) (CHEBI:68849)
Incoming Relation(s)
azilsartan medoxomil(1−) (CHEBI:68849) is conjugate base of azilsartan medoxomil (CHEBI:68845)
IUPAC Name 
(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 2-ethoxy-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl}-1-benzimidazole-7-carboxylate
INNs  Source
azilsartan medoxomilWHO MedNet
azilsartan médoxomilWHO MedNet
azilsartán medoxomiloWHO MedNet
azilsartanum medoxomilumWHO MedNet
Brand Name  Source
EdarbiChEBI
Manual XrefsDatabases
4322DrugCentral
AzilsartanWikipedia
D08067KEGG DRUG
US2005187269Patent
Registry NumbersSources
Reaxys:12326818Reaxys
CAS:863031-21-4KEGG DRUG
CAS:863031-21-4ChemIDplus
Citations