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CHEBI:45285 - pyrazinecarboxamide

ChEBI IDCHEBI:45285
ChEBI Namepyrazinecarboxamide
Stars
DefinitionA monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.
Secondary ChEBI IDsCHEBI:8656, CHEBI:45281
Last Modified12 January 2021
DownloadsMolfile
FormulaC5H5N3O
Net Charge0
Average Mass123.115
Monoisotopic Mass123.04326
SMILESNC(=O)c1cnccn1
InChIInChI=1S/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9)
InChIKeyIPEHBUMCGVEMRF-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Role:
antitubercular agent  A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis.
Applications:
antitubercular agent  A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis.
prodrug  A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
ChEBI Ontology
Outgoing Relation(s)
pyrazinecarboxamide (CHEBI:45285) has role antitubercular agent (CHEBI:33231)
pyrazinecarboxamide (CHEBI:45285) has role prodrug (CHEBI:50266)
pyrazinecarboxamide (CHEBI:45285) is a N-acylammonia (CHEBI:83628)
pyrazinecarboxamide (CHEBI:45285) is a monocarboxylic acid amide (CHEBI:29347)
pyrazinecarboxamide (CHEBI:45285) is a pyrazines (CHEBI:38314)
Incoming Relation(s)
N-butyl-5-(4-hydroxyphenyl)-6-oxo-1,6-dihydropyrazine-2-carboxamide (CHEBI:167182) is a pyrazinecarboxamide (CHEBI:45285)
IUPAC Name 
pyrazine-2-carboxamide
INNs  Source
pyrazinamidaWHO MedNet
pyrazinamidumWHO MedNet
pyrazinamideWHO MedNet
pyrazinamideWHO MedNet
Synonyms  Source
PyrazinamideKEGG COMPOUND
Pyrazinoic acid amideKEGG COMPOUND
2-carbamylpyrazineChemIDplus
pyrazine carboxamideNIST Chemistry WebBook
2-pyrazinecarboxamideChemIDplus
PYRAZINE-2-CARBOXAMIDEPDBeChem
UniProt Name  Source
pyrazinamideUniProt
Manual XrefsDatabases
C01956KEGG COMPOUND
PZAPDBeChem
PyrazinamideWikipedia
DB00339DrugBank
HMDB0014483HMDB
D00144KEGG DRUG
LSM-5425LINCS
2328DrugCentral
Registry NumbersSources
Beilstein:112306Beilstein
Gmelin:279021Gmelin
Reaxys:112306Reaxys
CAS:98-96-4KEGG COMPOUND
CAS:98-96-4ChemIDplus
CAS:98-96-4NIST Chemistry WebBook
Citations